Rapid Emergence of Florfenicol-Resistant Invasive Non-Typhoidal Salmonella in China: A Potential Threat to Public Health
文献类型： 外文期刊
作者： Zhan, Zeqiang 1 ; Xu, Xuebin 2 ; Shen, Haiyan 3 ; Gao, Yuan 1 ; Zeng, Fanliang 1 ; Qu, Xiaoyun 1 ; Zhang, Hongxia 1 ; Lia 1 ;
作者机构： 1.South China Agr Univ, Natl & Reg Joint Engn Lab Medicament Zoonoses Pre, Key Lab Zoonoses Prevent & Control Guangdong Prov, Anim Infect Dis Lab,Coll Vet Med,Minist Agr,Key L, Guangzhou, Guangdong, Peoples R China
2.Shanghai Municipal Ctr Dis Control & Prevent, Shanghai, Peoples R China
3.Guangdong Acad Agr Sci, Sci Observat & Expt Stn Vet Drugs & Diagnost Tech, Key Lab Livestock Dis Prevent Guangdong Prov, Minist Agr,Inst Anim Hlth, Guangzhou, Guangdong, Peoples R China
期刊名称：AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE （ 影响因子：2.345； 五年影响因子：2.799 ）
ISSN： 0002-9637
年卷期： 2019 年 101 卷 6 期
页码：
收录情况： SCI
摘要： Infection caused by invasive Salmonella occurs when Salmonella bacteria, which normally cause diarrhea, enter the bloodstream and spread through the body. We report the dramatic increase in florfenicol-resistant invasive non-typhoidal Salmonella (iNTS) in China between 2007 and 2016. Of the 186 iNTS strains isolated during the study period, 34 were florfenicol resistant, most of which harbored known resistance genes. Florfenicol is exclusively used in veterinary medicine in China, but now florfenicol-resistant iNTS is found in clinical patients. This finding indicates that antimicrobial resistance produced in veterinary medicine can be transmitted to humans, which poses a severe threat to public health.
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