Prevalence, genomic characteristics, and pathogenicity of fowl adenovirus 2 in Southern China
文献类型： 外文期刊
作者： Zhang, Junqin 1 ; Xie, Zimin 1 ; Pan, Yanlin 1 ; Chen, Zuoxin 1 ; Huang, Yunzhen 1 ; Li, Linlin 1 ; Dong, Jiawen 1 ; Xiang, Yong 1 ; Zhai, Qi 1 ; Sun, Minhua 1 ; Li, Xingying 6 ; Huang, Shujian 5 ; Liao, Ming 1 ;
作者机构： 1.Minist Agr & Rural Affairs, Guangdong Acad Agr Sci, Inst Anim Hlth, Key Lab prevent & control Avian fluenza & Other Ma, Guangzhou, Guangdong, Peoples R China
2.Key Lab Livestock Dis Prevent & Treatment Guangdon, Guangzhou, Guangdong, Peoples R China
3.South China Agr Univ, Guangzhou, Peoples R China
4.Zhongkai Univ Agr & Engn, Guangzhou, Peoples R China
5.Foshan Univ, Coll Life Sci & Engn, Foshan, Peoples R China
6.Guangdong VETCELL Biotech Co Ltd, Foshan, Peoples R China
关键词： fowl adenovirus 2; prevalence; complete genome; recombination; pathogenicity
期刊名称：POULTRY SCIENCE （ 影响因子：4.4； 五年影响因子：4.4 ）
ISSN： 0032-5791
年卷期： 2024 年 103 卷 1 期
页码：
收录情况： SCI
摘要： In recent years, the occurrence of fowl adenovirus 2 (FAdV-2) has been on the rise in China, posing a significant threat to the poultry industry. This study aimed to investigate the epidemiology, phylogenetic relationship, genomic characteristics, and pathogenicity of FAdV-2. The epidemiological analysis revealed the detection of multiple FAdV serotypes, including FAdV-1, FAdV-2, FAdV-3, FAdV-4, FAdV-8a, FAdV-8b, and FAdV-11 serotypes. Among them, FAdV-2 exhibited the highest proportion, accounting for 21.05% (8/38). The complete genomes of these 8 FAdV-2 strains were sequenced. Genetic evolution analysis indicated that these FAdV-2 strains formed a separate branch within the FAdV-D group, sharing 94.60 to 97.90% nucleotide similarity with the reference FAdV-2 and FAdV-11 strains. Notably, the recombination analysis revealed that 5 out of the 8 FAdV-2 strains, exhibited recombination events between FAdV-2 and FAdV-11. The recombination regions involved Hexon, Fiber, ORF19 genes and 30 end. Furthermore, pathogenicity experiments demonstrated that recombinant FAdV-2 XX strain is capable of inducing mortality rate of 66.70% and causing more severe hepatitis hydropericardium syndrome (HHS) in 6-wk-old specific-pathogen-free chickens. These findings contribute to our under-standing of the prevalence, genomic characteristics, and the pathogenicity of FAdV-2, providing foundations for FAdV-2 vaccine development.
- 相关文献
作者其他论文 更多>>
-
Influence of PepF peptidase and sporulation on microcin J25 production in Bacillus subtilis
作者：Zhang, Guangwen;Feng, Saixiang;Qin, Miaomiao;Sun, Juan;Liu, Yutong;Luo, Changqi;Lin, Min;Xu, Siqi;Liao, Ming;Fan, Huiying;Liang, Zhaoping;Feng, Saixiang;Liao, Ming;Fan, Huiying;Feng, Saixiang;Liao, Ming;Feng, Saixiang;Liao, Ming;Fan, Huiying;Feng, Saixiang;Liao, Ming;Fan, Huiying;Liao, Ming
关键词：microcin J25; peptidase; PepF; Bacillus subtilis; sporulation
-
The evolution, pathogenicity and transmissibility of quadruple reassortant H1N2 swine influenza virus in China: A potential threat to public health
作者：Cui, Xinxin;Ma, Jinhuan;Pang, Zifeng;Mai, Cuishan;Liu, Hanlin;Liao, Ming;Sun, Hailiang;Cui, Xinxin;Ma, Jinhuan;Pang, Zifeng;Mai, Cuishan;Liu, Hanlin;Liao, Ming;Sun, Hailiang;Cui, Xinxin;Ma, Jinhuan;Pang, Zifeng;Mai, Cuishan;Liu, Hanlin;Liao, Ming;Sun, Hailiang;Chi, Lingzhi;Liao, Ming
关键词：Swine influenza virus (SIV); Evolution; Replication; Pathogenicity; Zoonotic potential
-
First Report of a Novel Goose Adenovirus Outbreak in Lion Head Gooses in China
作者：Liu, Rongchang;Lan, Qin;Zhang, Jiaxue;Liang, Qizhang;Fu, Guanghua;Huang, Yu;Liu, Rongchang;Liao, Ming;Sun, Minhua;Liao, Ming;Sun, Minhua;Liao, Ming
关键词：
-
Influenza D virus infection in China, 2022-2023
作者：Yu, Jieshi;Wei, Wen-kang;Wen, Zhenyu;Liao, Ming;Hu, Wanke;Chen, Mingwang;Li, Tianyu;Zhang, Yuanlong;Liu, Shasha;Wang, Gang;Zhai, Shao-lun;Liao, Ming;Wang, Zhao;Wang, Dan;Li, Tianyu;Liao, Ming
关键词：Influenza D virus; phylogenetic lineage; seroprevalence; antigenic characterization
-
N-glycosylation on hemagglutinin head reveals inter-branch antigenic variability of avian influenza virus H5-subtypes
作者：Shi, Keyi;Feng, Saixiang;Zhao, Li;Chen, Junhong;Song, Wei;Jia, Yusheng;Qu, Xiaoyun;Jia, Weixin;Liao, Ming;Liu, Zhicheng;Du, Shouwen;Liao, Ming;Liao, Ming;Du, Shouwen
关键词：H5-subtype AIV; N-glycosylation; Antigenicity of hemagglutinin
-
An effective deep learning fusion method for predicting the TVB-N and TVC contents of chicken breasts using dual hyperspectral imaging systems
作者：Cai, Mingrui;Han, Yuxing;Li, Xiaoxin;Liang, Juntao;Liao, Ming;Li, Xiaoxin;Liang, Juntao;Liao, Ming;Liao, Ming
关键词：Chicken breast; Hyperspectral imaging techniques; Deep learning; Data fusion; Attention mechanism; Pyramid structure
-
IFITM3 inhibits severe fever with thrombocytopenia syndrome virus entry and interacts with viral Gc protein
作者：Du, Shouwen;Liu, Quan;Liao, Ming;Du, Shouwen;Zhou, Boping;Wang, Jigang;Wang, Yuhang;Wang, Jiamin;Ma, Yidan;Xu, Wang;Shi, Xiaoshuang;Li, Letian;Hao, Pengfei;Jin, Ningyi;Li, Chang;Wong, Yin K.;Wang, Jigang;Hu, Lifen;Liu, Wei
关键词：antiviral activity; Gc subunit; interferon-induced transmembrane protein 3; SFTSV; virus-IFITM3 interaction
