文献类型： 外文期刊
作者： Zhang, Tingting 1 ; Yuan, Dongwei 1 ; Xie, Jun 5 ; Lei, Yongxing 4 ; Li, Jianguo 7 ; Fang, Gangqi 3 ; Tian, Ling 8 ; Liu, 1 ;
作者机构： 1.South China Normal Univ, Inst Insect Sci & Technol, Sch Life Sci, Guangdong Prov Key Lab Insect Dev Biol & Appl Tec, Guangzhou, Guangdong, Peoples R China
2.Shanxi Univ, Res Inst Appl Biol, Taiyuan, Shanxi, Peoples R China
3.Chinese Acad Sci, CAS Ctr Excellence Mol Plant Sci, CAS Key Lab Insect Dev & Evolutionary Biol, Inst Plant Physiol & Ecol, Shanghai, Peoples R China
4.Univ Chinese Acad Sci, Beijing, Peoples R China
5.Fudan Univ, Inst Genet, Sch Life Sci, State Key Lab Genet Engn, Shanghai, Peoples R China
6.Chinese Acad Sci, Inst Plant Physiol & Ecol, Key Lab Synthet Biol, Shanghai, Peoples R China
7.Shanxi Univ, Inst Biomed Sci, Taiyuan, Shanxi, Peoples R China
8.South China Agr Univ, Guangdong Prov Key Lab Agroanim Genom & Mol Breed, Guangdong Prov Sericulture & Mulberry Engn Res Ct, Coll Anim Sci, Guangzhou, Guangdong, Peoples R China
9.Chinese Acad Sci, Shanghai Inst Biochem & Cell Biol, Innovat Ctr Cell Signaling Network, State Key Lab Mol Biol,CAS Ctr Excellence Mol Cel, Shanghai, Peoples R China
10.Chinese Acad Sci, Nanjing Inst Geol & Palaeontol, State Key Lab Paleobiol & Stratig, Nanjing, Jiangsu, Peoples R China
关键词： cholesterol biosynthesis pathway; gene loss; Ediacaran period; macroevolution
期刊名称：MOLECULAR BIOLOGY AND EVOLUTION （ 影响因子：16.24； 五年影响因子：18.67 ）
ISSN： 0737-4038
年卷期： 2019 年 36 卷 11 期
页码：
收录情况： SCI
摘要： Cholesterol plays essential roles in animal development and disease progression. Here, we characterize the evolutionary pattern of the canonical cholesterol biosynthesis pathway (CBP) in the animal kingdom using both genome-wide analyses and functional experiments. CBP genes in the basal metazoans were inherited from their last common eukaryotic ancestor and evolutionarily conserved for cholesterol biosynthesis. The genomes of both the basal metazoans and deuterostomes retain almost the full set of CBP genes, while Cnidaria and many protostomes have independently experienced multiple massive losses of CBP genes that might be due to the geologic events during the Ediacaran period, such as the appearance of an exogenous sterol supply and the frequent perturbation of ocean oxygenation. Meanwhile, the indispensable utilization processes of cholesterol potentially strengthened the maintenance of the complete set of CBP genes in vertebrates. These results strengthen both biotic and abiotic roles in the macroevolution of a biosynthesis pathway in animals.
- 相关文献
作者其他论文 更多>>
-
Selective breeding of cold-tolerant black soldier fly (Hermetia illucens) larvae: Gut microbial shifts and transcriptional patterns
作者：Ma, Chong;Huang, Zhijun;Feng, Xingbao;Cui, Ying;Duan, Xinyu;Zhu, Jianfeng;Hu, Wenfeng;Tian, Ling;Ma, Chong;Huang, Zhijun;Feng, Xingbao;Cui, Ying;Duan, Xinyu;Zhu, Jianfeng;Hu, Wenfeng;Tian, Ling;Tettamanti, Gianluca;Tettamanti, Gianluca;Hu, Wenfeng
关键词：Hermetia illucens L; Selective breeding; Cold tolerance; Intestinal microflora; Metagenome; Transcriptome
-
Free and bound phenolic profiles of Radix Puerariae Thomsonii from different growing regions and their bioactivities
作者：Li, Weixin;Zhang, Min;Zhang, Mingwei;Jia, Xuchao;Chen, Yanxia;Dong, Lihong;Huang, Fei;Ma, Qin;Zhao, Dong;Zhang, Ruifen
关键词：Radix puerariae thomsonii; Phenolic composition; Antioxidant activity; Alcohol metabolizing enzymes; Carbohydrate hydrolyzing enzymes
-
Structural elucidation, binding sites exploration and biological activities of bound phenolics from Radix Puerariae Thomsonii
作者：Li, Weixin;Zhang, Min;Zhang, Ruifen;Huang, Fei;Dong, Lihong;Jia, Xuchao;Zhang, Mingwei
关键词：Radix puerariae thomsonii; Bound phenolics; Antioxidant activity; Alcohol -metabolizing enzymes; Carbohydrate -hydrolyzing enzymes; Stepwise enzymatic hydrolysis
-
Atg1 phosphorylation is activated by AMPK and indispensable for autophagy induction in insects
作者：Zhao, Haigang;Long, Shihui;Liu, Suning;Yuan, Dongwei;Huang, Danyan;Li, Sheng;Li, Kang;Xu, Jing;Ma, Qiuqin;Li, Sheng;Tian, Ling;Li, Kang;Zhao, Haigang;Yuan, Dongwei;Zhao, Haigang;Yuan, Dongwei;Li, Sheng;Li, Kang;Wang, Guirong;Wang, Jian;Zhao, Haigang;Zhao, Haigang;Zhao, Haigang
关键词：Autophagy; BmAtg1c; DmAtg1; AMPK; Phosphorylation modification; Starvation; 20-Hydroxyecdysone
-
Reticulate evolution of the tertiary relict Osmanthus
作者：Li, Yongfu;Li, Xuan;Zhang, Min;Yang, Qinghua;Duan, Yifan;Wang, Xianrong;Nie, Shuai;Nie, Shuai;Nie, Shuai;Xu, Wenbin
关键词：phylogenomics; introgression; reticulate evolution; historical biogeography
-
CircMGA Depresses Myoblast Proliferation and Promotes Myotube Formation through miR-144-5p/FAP Signal
作者：Wang, Zhijun;Zhang, Min;Li, Kan;Chen, Yangfeng;Cai, Danfeng;Nie, Qinghua;Wang, Zhijun;Zhang, Min;Li, Kan;Chen, Yangfeng;Cai, Danfeng;Nie, Qinghua;Wang, Zhijun;Zhang, Min;Li, Kan;Chen, Yangfeng;Cai, Danfeng;Nie, Qinghua;Chen, Biao
关键词：myogenesis; chicken; circMGA; miR-144-5p; FAP; competing endogenous RNA
-
Two divergent haplotypes from a highly heterozygous lychee genome suggest independent domestication events for early and late-maturing cultivars
作者：Hu, Guibing;Feng, Junting;Liu, Chengming;Wu, Zhenxian;Li, Jiawei;Mai, Yingxiao;Chen, Chengjie;Zheng, Jiakun;Zhang, Yanqing;Fu, Jiaxin;Lai, Biao;Huang, Xuming;Chen, Houbin;Xia, Rui;Li, Jianguo;Xiang, Xu;Liu, Wei;Ou, Liangxi;Chen, Jiezhen;Yan, Qian;Wang, Jiabao;Sun, Jinhua;Li, Huanling;Salojarvi, Jarkko;Albert, Victor A.;Zhang, Jisen;Zhang, Xingtan;Tang, Haibao;Liang, Xinming;Fan, Guangyi;Liu, Xin;Jiang, Zide;Peng, Hongxiang;Yao, Lixian;Wai, Ching Man;Ming, Ray;Luo, Xinping;Lan, Tianying;Albert, Victor A.;Wei, Yongzan;McHale, Leah K.;McHale, Leah K.;Rolling, William;Guyot, Romain;Sankoff, David;Zheng, Chunfang
关键词：
