您好，欢迎访问中国水产科学研究院 机构知识库！
中国水产科学研究院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

High-density genetic linkage map and QTL fine mapping of growth and sex in snakehead (Channa argus)

文献类型： 外文期刊

作者： Liu, Haiyang 1 ; Luo, Qing 1 ; Ou, Mi 1 ; Zhu, Xinping 1 ; Zhao, Jian 1 ; Chen, Kunci 1 ;

作者机构： 1.Chinese Acad Fishery Sci, Pearl River Fisheries Res Inst, Key Lab Trop & Subtrop Fishery Resources Applicat, Minist Agr & Rural Affairs, Guangzhou 510380, Peoples R China

关键词： Snakehead; Linkage map; SNP; QTL; Comparative genomics; Sex; Growth; Candidate genes

期刊名称：AQUACULTURE （ 影响因子：4.242； 五年影响因子：4.723 ）

ISSN： 0044-8486

年卷期： 2020 年 519 卷

页码：

收录情况： SCI

摘要： High-density genetic linkage maps are essential for quantitative trait locus (QTL) mapping, candidate gene identification, marker-assisted selection, genome assembly and comparative genomic analysis in aquaculture species. Snakehead (Channa argus) is an important aquaculture species in China, but the genetic improvement of this species is still in its infancy. In this study, a high-density genetic linkage map was constructed for snakehead using 2b-RAD sequencing technology. The consensus map contains 3151 single nucleotide polymorphism (SNP) markers assigned to 24 linkage groups (LGs) and spanning 2728.9 cM with an average marker interval of 0.87 cM. Comparative genomics revealed a 1:1 syntenic relationship between snakehead LGs and chromosomes of medaka and European seabass. Fourteen chromosome-wide QTLs associated with body weight and body length were identified in five LGs, explaining 9.6-12.8% of the phenotypic variation. Potential candidate growth-related genes, such as SATB homeobox 2 (satb2), were identified within the QTL intervals. A single major locus for sex determination was identified in LG5 that explained 97.4-100% of the phenotypic variation. Six markers with a sex-determining locus were found to be heterogametic in males and homogametic in females. A sex-specific SNP marker located in the sex QTL region was validated for practical verification of sex in snakehead. All of the results suggest an XX/XY sex determination system in this species. This high-density genetic map and QTL analysis supply a basis for genome evolutionary studies, genome assembly and QTL fine mapping of complex traits in snakehead.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国水产科学研究院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台