Synthesis and antifungal activity of novel pyrazolines and isoxazolines derived from cuminaldehyde
文献类型： 外文期刊
作者： Zhang, Tao 1 ; Dong, Mengya 2 ; Zhao, Jianjiang 1 ; Zhang, Xiaofang 1 ; Mei, Xiangdong 2 ;
作者机构： 1.Hebei Acad Agr & Forestry Sci, Integrated Pest Management Ctr Hebei Prov, Key Lab IPM Crops Northern Reg North China, Inst Plant Protect,Minist Agr, Baoding 071000, Peoples R China
2.Chinese Acad Agr Sci, Inst Plant Protect, State Key Lab Biol Plant Dis & Insect Pests, Beijing 100193, Peoples R China
关键词： cumin; cuminaldehyde; pyrazoline; isoxazoline; antifungal activity
期刊名称：JOURNAL OF PESTICIDE SCIENCE （ 影响因子：1.519； 五年影响因子：1.596 ）
ISSN： 1348-589X
年卷期： 2019 年 44 卷 3-4 期
页码：
收录情况： SCI
摘要： Two series of novel cuminaldehyde derivatives containing pyrazoline and isoxazoline moieties have been designed and synthesized. All of the compounds were characterized via H-1-NMR, C-13-NMR, and HRMS. The antifungal activities were evaluated against six plant-pathogenic fungi. 3-(2-Fluorophenyl) 5-(4-isopropylphenyl) isoxazoline (2d) and 1-acetyl-3-(2-fluoropheny1)-5-(4-isopropylpheny1)-2 -pyrazoline (3d) displayed higher antifungal activities than commercial fungicides against Sclerotinia sclerotiorum, Physalospora piricola and Pyricularia oryzae. The title compounds (2d and 3d) with strong antifungal activities are worth being further evaluated in vivo and in the field. (C) Pesticide Science Society of Japan
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