A review on furan: Formation, analysis, occurrence, carcinogenicity, genotoxicity and reduction methods
文献类型： 外文期刊
作者： Batool, Zahra 1 ; Xu, Dan 1 ; Zhang, Xia 1 ; Li, Xiaoxi 1 ; Li, Yuting 2 ; Chen, Zhiyi 3 ; Li, Bing 1 ; Li, Lin 1 ;
作者机构： 1.South China Univ Technol, Guangdong Prov Key Lab Green Proc Nat Prod & Prod, Sch Food Sci & Engn, Guangzhou 510640, Peoples R China
2.Dongguan Univ Technol, Sch Chem Engn & Energy Technol, Dongguan, Peoples R China
3.Guangdong Acad Agr Sci, Guangdong Key Lab Agr Prod Proc, Sericultural & Agri Food Res Inst, Key Lab Funct Foods,Minist Agr & Rural Affairs, Guangzhou, Peoples R China
关键词： Furan; formation mechanism; Maillard reaction; toxicity; reduction
期刊名称：CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION （ 影响因子：11.176； 五年影响因子：11.193 ）
ISSN： 1040-8398
年卷期：
页码：
收录情况： SCI
摘要： Furan (C4H4O) is a volatile, heterocyclic and carcinogenic heterocyclic chemical compound occurring in a wide range of thermally processed foods. Several studies have been conducted to analyze the formation conditions, triggering furan formation via model systems. Furan can be encountered via various pathways including thermal degradation, oxidation of polyunsaturated fatty acids, thermal rearrangement of carbohydrates in the presence of amino acids, thermal degradation of certain amino acids. Furan has been proven to cause cancer in experimental animal models and classified as a possible human carcinogen by International agency for research on cancer based on sufficient evidences. Thus, different strategies should be developed to reduce furan contents in commercially available food stuffs while food processing. This review summarizes some current evidences of furan formation from different precursors, analytical methods for its detection, and its toxicity that might lead to carcinogenicity and genotoxicity with human risk assessment. In addition, furan occurrence in different thermally processed foods entailed by several recent studies as well as furan mitigation strategies during food processing have also been illustrated in this review.
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