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A comparative study of the antioxidant and intestinal protective effects of extracts from different parts of Java tea (Orthosiphon stamineus)

文献类型： 外文期刊

作者： Cai, Xuan 1 ; Xiao, Changfeng 1 ; Xue, Huiqin 1 ; Xiong, Huihui 1 ; Hang, Yiqiong 1 ; Xu, Jianxiong 3 ; Lu, Yonghong 1 ;

作者机构： 1.Shanghai Shenfeng Anim Husb & Vet Sci Technol Co, Shanghai, Peoples R China

2.Shanghai Acad Agr Sci, Inst Anim Husb & Vet Sci, Shanghai, Peoples R China

3.Shanghai Jiao Tong Univ, Sch Agr & Biol, Shanghai, Peoples R China

关键词： antioxidant; intestinal epithelial cell; Java tea; mice; Orthosiphon stamineus

期刊名称：FOOD SCIENCE & NUTRITION （ 影响因子：2.863； 五年影响因子：3.141 ）

ISSN： 2048-7177

年卷期： 2018 年 6 卷 3 期

页码：

收录情况： SCI

摘要： The aim of this study was to compare the free radical scavenging ability and intestinal epithelial cell protective effects of Java tea (Orthosiphon stamineus) root extracts (ORE), stem extracts (OSE), and leaf extracts (OLE) to determine the potential of Java tea by-products. The Java tea extracts were prepared using a standard water-ethanol method. The antioxidant activity and intestinal protective effects were tested by H2O2-induced cell model and high-fat diet-induced mice model, respectively. The results showed that the total phenolic acid and flavonoid content and relative content were different in the ORE, OSE, and OLE. ORE had the highest total polyphenol and flavonoid content, the highest free radical scavenging rate, and the highest intracellular free radical scavenging rate. However, the yeast content in the ORE was lower than that in the OSE and OLE. All the Java tea extracts protected mouse intestine from high-fat diet-induced oxidative injury. This study indicates the potential of Java tea extracts as food or feed additives to protect the intestine from oxidative stress.

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