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A signal-enhanced lateral flow strip biosensor for ultrasensitive and on-site detection of bisphenol A

文献类型： 外文期刊

作者： Peng, Xiayu 1 ; Kang, Lichao 1 ; Pang, Fangqin 2 ; Li, Hongmin 2 ; Luo, Ruifeng 2 ; Luo, Xiaoling 1 ; Sun, Fengxia 1 ;

作者机构： 1.State Key Lab Sheep Genet Improvement & Hlth Bree, Shihezi 832000, Peoples R China

2.Xinjiang Acad Agr & Reclamat Sci, Anal & Testing Ctr, Shihezi 832000, Peoples R China

关键词： Lateral flow strip; signal amplification; BPA; food safety

期刊名称：FOOD AND AGRICULTURAL IMMUNOLOGY （ 影响因子：3.101； 五年影响因子：2.573 ）

ISSN： 0954-0105

年卷期： 2018 年 29 卷 1 期

页码：

收录情况： SCI

摘要： A signal-enhanced lateral flow strip biosensor has been constructed for ultrasensitive and on-site visual detection of bisphenol A (BPA). The signal amplification principle is based on the capacity of binding a large number of antibody-assembled gold nanoparticle (AuNP-antibody) conjugates of the poly amidoamine (PAMAM), which bears a multitude of amino groups. This signal-enhanced method could achieve BPA detection at 10ppb based on naked eye visual observation, which represents an at least 50-fold improvement of the sensitivity of a traditional method without PAMAM. Moreover, good linearity was observed in the range from 2 to 100ppb after quantitative analysis using the ImageJ software. This signal amplification method could be adopted as a potential generous technique in different fields.

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