您好，欢迎访问中国水产科学研究院 机构知识库！
中国水产科学研究院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

New locus reveals the genetic architecture of sex reversal in the Chinese tongue sole (Cynoglossus semilaevis)

文献类型： 外文期刊

作者： Cui, Yu 1 ; Wang, Weifeng 2 ; Ma, Liyong 4 ; Jie, Jinhua 5 ; Zhang, Yanhong 5 ; Wang, Huanling 3 ; Li, Hengde 2 ;

作者机构： 1.Shanghai Ocean Univ, Natl Demonstrat Ctr Expt Fisheries Sci Educ, Shanghai 201306, Peoples R China

2.Chinese Acad Fishery Sci, Ctr Appl Aquat Genom, Beijing 100141, Peoples R China

3.Huazhong Agr Univ, Coll Fisheries, Wuhan 430070, Hubei, Peoples R China

4.Hanhai Aqua Co Ltd, Weifang 261311, Shangdong Provi, Peoples R China

5.Jiehai Aqua Co Ltd China Czech High Tech Pk, Cangzhou 061108, Peoples R China

6.Chinese Acad Fishery Sci, CAFS Key Lab Aquat Genom, Minist Agr, Key Lab Aquat Genom, Beijing 100141, Peoples R China

7.Chinese Acad Fishery Sci, Beijing Key Lab Fishery Biotechnol, Beijing 100141, Peoples R China

期刊名称：HEREDITY （ 影响因子：3.821； 五年影响因子：4.553 ）

ISSN： 0018-067X

年卷期： 2018 年 121 卷 4 期

页码：

收录情况： SCI

摘要： Sex reversal in insects, amphibians, reptiles, and fishes is a complicated and interesting biological phenomenon. Sex reversal changes the sex ratio of populations and may complicate breeding schemes. In the Chinese tongue sole (Cynoglossus semilaevis), genetic females may change into pseudomales, thereby increasing aquaculture costs because of the lower growth rate of the males than that of the females. Here we identify a new locus associated with sex reversal; this single nucleotide polymorphism (SNP) is located in the third intron of the doublesex and mab-3 related transcription factor 1 (Dmrt1) gene on the Z chromosome (named Cyn_Z_8564889) and has two alleles, A and G. Cyn_Z_8564889 regulates sex reversal interactively with our previously detected SNP (Cyn_Z_6676874), with the genetic females simultaneously carrying the T allele of Cyn_Z_6676874 and the A allele of Cyn_Z_8564889 changing into pseudomales. Other Dmrt1 polymorphisms were detected, which formed two haplotypes. Two SNPs in the second exon of Dmrt1 result in amino acid changes, suggesting that Dmrt1 is essential in sex reversal. We also verified that pseudomales produce no or little W sperm. The interaction and linkage between Cyn_Z_6676874 and Cyn_Z_8564889 and the absence of W sperm from pseudomales unravel the genetic architecture of sex reversal in C. semilaevis.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国水产科学研究院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台