文献类型： 外文期刊
作者： Wang, Zhijun 1 ; Ouyang, Hongfia 1 ; Chen, Xiaolan 1 ; Yu, Jiao 1 ; Abdallat, Bahareldin A. 1 ; Chen, Biao 1 ; Nie, Qi 1 ;
作者机构： 1.South China Agr Univ, Coll Anim Sci, Dept Anim Genet Breeding & Reprod, Guangzhou, Guangdong, Peoples R China
2.Minist Agr, Guangdong Prov Key Lab Agroanim Genom & Mol Breed, Guangzhou, Guangdong, Peoples R China
3.Minist Agr, Key Lab Chicken Genet, Guangzhou, Guangdong, Peoples R China
4.Natl Local Joint Engn Res Ctr Livestock Breeding, Guangzhou, Guangdong, Peoples R China
5.Zhongkai Univ Agr & Engn, Coll Anim Sci & Technol, Guangzhou, Guangdong, Peoples R China
关键词： miR-205a; CDH11; myoblast; myogenesis; promoter active region
期刊名称：FRONTIERS IN GENETICS （ 影响因子：4.599； 五年影响因子：4.888 ）
ISSN： 1664-8021
年卷期： 2018 年 9 卷
页码：
收录情况： SCI
摘要： Non-coding RNAs especially miRNAs have been found to play important roles during skeletal muscle development. Our previous RNA-Seq performed on breast muscle tissue from 7 weeks old Recessive White Rock and Xinhua Chicken and leg muscle tissue from female Xinghua Chicken at three development time points (11 embryo age, 16 embryo age, and 1 day post hatch) (accession number GSE62971 and GSE89355, respectively) showed that miR-205a and CDH11 were differentially expressed genes. In this study, we found that overexpression of CDH11 significantly facilitated Quail muscle clone (QM7) and chicken primary myoblast (CPM) proliferation and hampered CPM differentiation. MiR-205a can directly binding to the 3'UTR of CDH11 and the overexpression of miR-205a could inhibit both cell lines (QM7) and CPM proliferation, at the meantime promote the differentiation of myoblasts. The Dual-Luciferase Reporter Assay results and qRT-PCR results showed that myogenin (MyoG) could regulate the expression of miR-205a by binding to the active region of miR-205a. Altogether our data suggest that MyoG could stimulate miR-205a expression to suppress CDH11, which promotes myoblasts proliferation while represses the differentiation.
- 相关文献
作者其他论文 更多>>
-
Exploring variances in meat quality between Qingyuan partridge chicken and Cobb broiler: Insights from combined multi-omics analysis
作者：Yang, Xin;Cai, Bolin;Zhang, Zhaofeng;Mo, Yu;Zhou, Zhen;Wu, Ruiquan;Kong, Shaofen;Cai, Danfeng;Zhang, Ruitong;Li, Zhenhui;Nie, Qinghua;Yang, Xin;Cai, Bolin;Zhang, Zhaofeng;Mo, Yu;Zhou, Zhen;Wu, Ruiquan;Kong, Shaofen;Cai, Danfeng;Li, Zhenhui;Nie, Qinghua
关键词：Qingyuan partridge chicken; Commercial broiler; Meat quality; Multi-omics analysis
-
METTL3-dependent m6A modification of GHR mRNA regulates mitochondrial function through mitochondrial biogenesis during myoblast differentiation
作者：Zhao, Changbin;Hu, Bowen;Wang, Zhijun;Zhang, Ze;Luo, Wen;Li, Hongmei;Zhang, Xiquan;Zhao, Changbin;Hu, Bowen;Wang, Zhijun;Zhang, Ze;Luo, Wen;Li, Hongmei;Zhang, Xiquan;Zhao, Changbin;Hu, Bowen;Wang, Zhijun;Zhang, Ze;Luo, Wen;Li, Hongmei;Zhang, Xiquan
关键词：GHR; METTL3; m6A; Mitochondrial biogenesis; Mitochondrial function
-
G-Quadruplexes in Gene Regulation and Cellular Function
作者：Guo, Lijin;Nie, Qinghua
关键词：diseases; function; G-quadruplex; structure
-
Skeletal muscle myopathies and cardiovascular diseases in poultry: challenges for meat production
作者：Bordbar, Farhad;Wadood, Armughan Ahmed;Nie, Qinghua;Guo, Wei
关键词：Poultry; muscle growth; meat quality; muscle myopathy; cardiomyopathy
-
Changes in gut microbiota affect DNA methylation levels and development of chicken muscle tissue
作者：Xu, Yibin;Huang, Yunpeng;Wei, Shenghua;Tian, Jinghong;Nie, Qinghua;Zhang, Dexiang;Xu, Yibin;Huang, Yunpeng;Wei, Shenghua;Tian, Jinghong;Nie, Qinghua;Zhang, Dexiang;Xu, Yibin;Huang, Yunpeng;Wei, Shenghua;Tian, Jinghong;Nie, Qinghua;Zhang, Dexiang;Xu, Yibin;Huang, Yunpeng;Wei, Shenghua;Tian, Jinghong;Nie, Qinghua;Zhang, Dexiang;Huang, Yulin;Zhang, Dexiang
关键词：Gut microbiome; Yellow-feathered chicken; Growth and development; DNA methylation
-
Improvement of the accuracy of breeding value prediction for egg production traits in Muscovy duck using low-coverage whole-genome sequence data
作者：Ye, Haoqiang;Liu, Xiaoqi;Bello, Semiu Folaniyi;Guo, Lijin;Fang, Xiang;Lin, Duo;Mo, Yu;Lei, Zhilin;Cai, Bolin;Nie, Qinghua;Ye, Haoqiang;Liu, Xiaoqi;Bello, Semiu Folaniyi;Guo, Lijin;Fang, Xiang;Lin, Duo;Mo, Yu;Lei, Zhilin;Cai, Bolin;Nie, Qinghua;Ye, Haoqiang;Liu, Xiaoqi;Bello, Semiu Folaniyi;Guo, Lijin;Fang, Xiang;Lin, Duo;Mo, Yu;Lei, Zhilin;Cai, Bolin;Nie, Qinghua;Ji, Congliang;Bello, Semiu Folaniyi
关键词：Muscovy duck; Low-coverage whole genome sequencing; Genomic prediction; Egg production traits; Linkage disequilibrium
-
Genetic regulation of gene expression across multiple tissues in chickens
作者：Guan, Dailu;Wang, Ying;Zhou, Huaijun;Bai, Zhonghao;Zhu, Di;Li, Houcheng;Buitenhuis, Albert Johannes;Sahana, Goutam;Lund, Mogens Sando;Fang, Lingzhao;Zhu, Xiaoning;Zhu, Di;Wang, Yuzhe;Hu, Xiaoxiang;Zhong, Conghao;Lan, Fangren;Li, Xiaochang;Sun, Congjiao;Yang, Ning;Zhong, Conghao;Lan, Fangren;Li, Xiaochang;Sun, Congjiao;Yang, Ning;Hou, Yali;Pan, Zhangyuan;Si, Wei;Diao, Shuqi;Gao, Yahui;Teng, Jinyan;Xu, Zhiting;Lin, Qing;Li, Zhenhui;Nie, Qinghua;Zhang, Xiquan;Zhang, Zhe;Yao, Yuelin;Yao, Yuelin;Zhao, Bingru;Gao, Yahui;Liu, George E.;Gao, Yahui;Zou, Dong;Wang, Ruizhen;Xu, Tianyi;Zhang, Zhang;Zou, Dong;Wang, Ruizhen;Xu, Tianyi;Zhang, Zhang;Wang, Ruizhen;Zhang, Zhang;Yin, Hongwei;Shi, Shourong;Shao, Dan;Degalez, Fabien;Lagarrigue, Sandrine;Wang, Mingshan;Peng, Minsheng;Wang, Mingshan;Peng, Minsheng;Rocha, Dominique;Charles, Mathieu;Smith, Jacqueline;Watson, Kellie;Warren, Wesley;Frantz, Laurent;Frantz, Laurent;Larson, Greger;Lamont, Susan J.;Si, Wei;Zhao, Xin;Li, Bingjie;Zhang, Haihan;Luo, Chenglong;Shu, Dingming;Qu, Hao;Luo, Wei;Li, Zhenhui;Nie, Qinghua;Zhang, Xiquan;Li, Zhenhui;Nie, Qinghua;Zhang, Xiquan;Xiang, Ruidong;Xiang, Ruidong;Xiang, Ruidong;Liu, Shuli;Cheng, Hans
关键词：
