文献类型： 外文期刊
作者： Liu, Shou-Bai 1 ; Mei, Wen-Li 1 ; Chen, Hui-Qin 1 ; Wang, Jun 1 ; Wang, Zhu-Nian 2 ; Dai, Hao-Fu 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Lab Biol & Genet Resources Trop Crops, Haikou 571101, Hainan, Peoples R China
2.Chinese Acad Trop Agr Sci, Trop Crops Genet Resources Inst, Danzhou 571737, Peoples R China
关键词： Trichilia sinensis; Roots; Trichilin-type limonoids; Cytotoxic activities
期刊名称：ARCHIVES OF PHARMACAL RESEARCH （ 影响因子：4.946； 五年影响因子：3.483 ）
ISSN： 0253-6269
年卷期： 2018 年 41 卷 12 期
页码：
收录情况： SCI
摘要： Six new compounds (1-4, 8, 10), along with six known limonoids (5-7, 9, 11, 12), were isolated from the roots of Trichilia sinensis. Their structures were elucidated on the basis of extensive spectroscopic methods including H-1 NMR, C-13 NMR, DEPT, HSQC, HMBC, H-1-H-1 COSY and ROESY experiments, as well as by comparison with the literature. All the compounds were evaluated for cytotoxicities against K562, SGC-7901 and BEL-7402 cell lines. Compounds 2, 7, 10, 11, and 12 showed weak inhibitory activity to the selected cell lines.
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