New Isocoumarins from an Endophytic Fungal Strain Diaporthe arengae M2 and their Antibacterial Activities
文献类型： 外文期刊
作者： Liu, De-Sui 1 ; Ma, Qing-Yun 1 ; Yang, Li 1 ; Xie, Qing-Yi 1 ; Wu, You-Gen 4 ; Dai, Hao-Fu 1 ; Zhang, Jun-Feng 3 ; Zhao, You-Xing 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Haikou Key Lab Res & Utilizat Trop Nat Prod, Haikou 571101, Hainan, Peoples R China
2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Natl Key Lab Trop Crop Breeding, Haikou 571101, Hainan, Peoples R China
3.Hainan Univ, Sch Chem & Chem Engn, Haikou 570228, Hainan, Peoples R China
4.Hainan Univ, Sanya Nanfan Res Inst, Hainan Yazhou Bay Seed Lab, Sanya 572025, Hainan, Peoples R China
关键词：
Endophytic fungi;
期刊名称：CHEMISTRY & BIODIVERSITY （ 影响因子：2.5； 五年影响因子：2.6 ）
ISSN： 1612-1872
年卷期： 2025 年 22 卷 3 期
页码：
收录情况： SCI
摘要： Four new isocoumarin derivatives 12-O-acetyl-isocitreoisocoumarinol (1), (+)-(10R)-O-acetyl-diaportinol (2-a), (-)-(10S)-O-acetyl-diaportinol (2-b), peyroisocoumarin E (3) and new stereoconfigurations of three isocoumarin derivatives desmethyldichlorodiaportinol A (4), threo-monochlorodiaportinol A (5-a), erytheo-monochlorodiaportinol A (5-b), together with nine known ones (6-14), were separated from the rice fermentation of endophytic fungus Diaporthe arengae M2 isolated from Camellia oleifera. The structures of new compounds were determined by extensive spectroscopic analyses including nuclear magnetic resonance (NMR) and high resolution electrospray ionization mass spectroscopy (HR-ESI-MS). Compounds 4, 7, 8, 12, 13 exhibited definite inhibition against five strains of bacteria with the MIC values range from 16 mu g/mL to 64 mu g/mL.
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