文献类型： 外文期刊
作者： Yan, Xian-Yun 1 ; Li, Wei 2 ; Wang, Hao 2 ; Dong, Wen-Hua 2 ; Zeng, Jun 2 ; Wu, Fei 2 ; Mei, Wen-Li 2 ; Liang, Lin-Fu 1 ; Dai, Hao-Fu 2 ;
作者机构： 1.Cent South Univ Forestry & Technol, Coll Chem & Chem Engn, Changsha 410004, Peoples R China
2.Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Natl Key Lab Trop Crop Breeding, Haikou 571101, Peoples R China
3.Int Joint Res Ctr Agarwood, Haikou 571101, Peoples R China
关键词： Agarwood; Aquilaria malaccensis; 2-(2-phenethyl)chromone dimers; Anti-inflammatory activity
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.4； 五年影响因子：1.5 ）
ISSN： 1874-3900
年卷期： 2025 年 66 卷
页码：
收录情况： SCI
摘要： Three unreported 2-(2-phenethyl)chromone dimers, malaccenones A-C (1-3), were isolated and identified from the agarwood Aquilaria malaccensis. These compounds were purified by various column chromatographic techniques, and their structures were elucidated based on the analysis of UV, HRESIMS, 1D and 2D NMR, and ECD spectroscopic data, as well as comparison with literature data. Compounds 1-3 were evaluated for their inhibition effects on nitric oxide production in lipopolysaccharide-stimulated RAW264.7 cells. All of these compounds exhibited anti-inflammatory activity with IC50 values ranging from 21.79 +/- 1.05-31.44 +/- 1.65 mu M.
- 相关文献
作者其他论文 更多>>
-
Identification of targets and comparative study of administration methods for the lipid-lowering effects of fucoidan from Saccharina japonica
作者：Chen, Pengwei;Wang, Hao;Chen, Huiqin;Dai, Haofu;Hao, Li;Li, Quancai;Zhang, Miao;Jiang, Hongfei;Zhang, Renshuai;Jia, Ang
关键词：Fucoidan; Lipid-lowering activity; Dietary supplementation; Intestinal target; Gut microbiota
-
New Isocoumarins from an Endophytic Fungal Strain Diaporthe arengae M2 and their Antibacterial Activities
作者：Liu, De-Sui;Ma, Qing-Yun;Yang, Li;Xie, Qing-Yi;Dai, Hao-Fu;Zhao, You-Xing;Liu, De-Sui;Ma, Qing-Yun;Yang, Li;Xie, Qing-Yi;Dai, Hao-Fu;Zhao, You-Xing;Liu, De-Sui;Zhang, Jun-Feng;Wu, You-Gen
关键词：Endophytic fungi;
Diaporthe sp.; Isocoumarin derivatives; Antibacterial activity -
Comprehensive analysis of morphology, transcriptomics, and metabolomics of banana (Musa spp.) molecular mechanisms related to plant height
作者：Wei, Junya;Cheng, Shimin;Huang, Lina;Wei, Shouxing;Liu, Guoyin;Sun, Mingzhen;Wang, Hao;Liu, Debing;Yang, Ping
关键词：banana; metabolomics; transcriptomics; hormones; height
-
2-(2-Phenylethyl)chromone-Sesquiterpene Hybrids from Agarwood of Aquilaria sinensis: Characterization and Biological Activity Evaluation
作者：Xu, Guan-Hua;Liu, Shou-Bai;Xu, Guan-Hua;Wang, Ya-Li;Wang, Hao;Chen, Hui-Qin;Dong, Wen-Hua;Huang, Sheng-Zhuo;Cai, Cai-Hong;Yuan, Jing-Zhe;Mei, Wen-Li;Dai, Hao-Fu
关键词：Hainan agarwood; 2-(2-phenylethyl)chromone-sesquiterpene hybrids; structure elucidation; anti-inflammatory activity; neuroprotective activity; cytotoxic activity
-
Comprehensive investigation of the C2H2-type zinc finger protein transcription factor family in Aquilaria sinensis reveals the involvement of AsZFP9 in sesquiterpene biosynthesis
作者：Li, Yuji;Guo, Dong;Wang, Hao;Wang, Ying;Peng, Shiqing;Dai, Haofu;Mei, Wenli;Zhu, Jiahong;Guo, Dong;Dai, Haofu;Zhu, Jiahong;Li, Yuji;Wang, Hao;Peng, Shiqing;Dai, Haofu;Mei, Wenli
关键词：Aquilaria sinensis; Zinc finger protein; Agarwood; Sesquiterpene biosynthesis
-
Nauclofficines A and B, two novel monoterpenoid indole alkaloids from the Li folk herb Nauclea officinalis with anti-allergic inflammatory effects on RBL-2H3 cells
作者：Li, Yan-li;Wang, Ting;Wang, Hao;Wang, Qi;Cai, Cai-Hong;Mei, Wen-Li;Dai, Hao-Fu;Huang, Sheng-Zhuo;Dai, Hao-Fu;Huang, Sheng-Zhuo;Li, Yan-li;Xu, Feng-Qing;Wang, Ting;Zhu, Guo-Peng
关键词：Nauclea officinalis; Monoterpenoid indole alkaloid; Li folk medicine; Anti-inflammatory activity; Nauclofficine
-
Development of Subcritical Water Extraction for Areca Alkaloids and Its Influence on the Structure of Areca Nut Husk
作者：Zhao, Hongliang;Zhou, Bosheng;Yang, Xiaohong;Sun, Ranfeng;Zhao, Hongliang;Yang, Jinghao;Zeng, Jun;Yang, Min
关键词：subcritical water extraction; areca nut; alkaloid; husk; fiber
