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Autophagy in Ovarian Follicular Development and Atresia

文献类型: 外文期刊

作者: Zhou, Jiawei 1 ; Peng, Xianwen 1 ; Mei, Shuqi 1 ;

作者机构: 1.Hubei Acad Agr Sci, Inst Anim Sci & Vet Med, Wuhan 430064, Hubei, Peoples R China

2.Hubei Key Lab Anim Embryo Engn & Mol Breeding, Wuhan 430064, Hubei, Peoples R China

关键词: autophagy; follicular development; atresia; granulosa cells

期刊名称:INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES ( 影响因子:6.58; 五年影响因子:6.478 )

ISSN: 1449-2288

年卷期: 2019 年 15 卷 4 期

页码:

收录情况: SCI

摘要: Autophagy is a mechanism that exists in all eukaryotes under a variety of physiological and pathological conditions. In the mammalian ovaries, less than 1% of follicles ovulate, whereas the remaining 99% undergo follicular atresia. Autophagy and apoptosis have been previously found to be involved in the regulation of both primordial follicular development as well as atresia. The relationship between autophagy, follicular development, and atresia have been summarized in this review with the aim to obtain a more comprehensive understanding of the role played by autophagy in follicular development and atresia.

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