Optimization of degradation conditions and elucidation of novel biodegradation pathways for sulfamonomethoxine by a novel Bacillus strain
文献类型： 外文期刊
作者： Wang, Xiujuan 1 ; Li, Jingtong 3 ; Chen, Chunyan 4 ; Luo, Zifeng 1 ; Pang, Yuwan 5 ; Tu, Hongxing 1 ; Lin, Xiaojun 1 ; Long, Cuifen 7 ; Cai, Qianyi 1 ; Wei, Zebin 1 ; Qiu, Jinrong 1 ;
作者机构： 1.MEE, South China Inst Environm Sci, Guangzhou, Peoples R China
2.State Environm Protect Key Lab Water Environm Simu, Guangzhou, Guangdong, Peoples R China
3.Yangtze Univ, Coll Agr, Jingzhou, Hubei, Peoples R China
4.Jinan Univ, Guangzhou, Peoples R China
5.Guangdong Acad Agr Sci, Inst Agr Resources & Environm, Guangzhou, Peoples R China
6.South China Agr Univ, Coll Nat Resources & Environm, Guangzhou, Peoples R China
7.Guangzhou Municipal River & Channel Monitoring Ctr, Guangzhou, Guangdong, Peoples R China
关键词：
sulfamonomethoxine (SMM);
期刊名称：APPLIED AND ENVIRONMENTAL MICROBIOLOGY （ 影响因子：3.7； 五年影响因子：4.5 ）
ISSN： 0099-2240
年卷期： 2025 年
页码：
收录情况： SCI
摘要： As a commonly used sulfonamide antibiotic, the efficient reduction of sulfamonomethoxine (SMM) residue in the environment is a critical issue that urgently needs to be addressed. However, there is limited understanding of the microbial conditions needed for efficient SMM degradation and its mechanisms. Therefore, this study screened a new strain, Bacillus sp. DLY-11, from swine manure compost with significant SMM degradation capability, and utilized response surface methodology (RSM) based on Box-Behnken design to optimize the degradation conditions. The results showed that under conditions of a 5% inoculation volume, a temperature of 59.1 degrees C, a pH value of 7.10, and 0.45 g/L MgSO4, strain DLY-11 could degrade 98.8% of 20 mg/L SMM within 48 h. Product analysis identified six potential transformation products and proposed two potential biodegradation pathways of SMM, including C-N bond cleavage, hydroxylation, and SO2 release. Particularly, we discovered a novel degradation pathway that has not been reported before. This study not only introduced a new strain for efficient SMM degradation but also optimized conditions and revealed new degradation pathways. These findings addressed gaps in bacterial SMM degradation pathways, offering theoretical and technical support for bioremediating antibiotic pollutants in animal husbandry.IMPORTANCEThe discovery of a new Bacillus sp., strain DLY-11, from aerobically composted swine manure offers significant environmental benefits by efficiently degrading 98.8% of 20 mg/L sulfamonomethoxine (SMM) within 48 hours under optimal conditions (5% inoculation volume, 59.1 degrees C, pH 7.10, 0.45 g/L MgSO4). This strain introduces a new tool for reducing SMM antibiotic pollution and reveals a novel degradation pathway, enhancing our understanding of SMM biodegradation mechanisms and supporting targeted bioremediation strategies.
- 相关文献
作者其他论文 更多>>
-
Impacts of the combined application of digestate-based compost and biochar on the heavy metal Cd distribution and stress in the plant-soil system
作者：Zhen, Feng;Xing, Tao;Zhou, Hengbing;Han, Linpei;Zhang, Yifan;Li, Lei;Zhen, Feng;Xing, Tao;Pang, Yuwan
关键词：Digestate-based compost; Biochar; Cadmium-contaminated soil; Plant-soil system; Microbial community
-
Response surface methodology and Box-Behnken design optimization of Sulfaquinoxaline removal efficiency and degradation mechanisms by Bacillus sp. strain DLY-11
作者：Chen, Chunyan;Luo, Zifeng;Tu, Hongxing;Lin, Xiaojun;Wang, Xiujuan;Cai, Qianyi;Zeng, Jingwen;Qiu, Jinrong;Luo, Zifeng;Tu, Hongxing;Lin, Xiaojun;Wang, Xiujuan;Cai, Qianyi;Zeng, Jingwen;Qiu, Jinrong;Pang, Yuwan;Huang, Jianfeng;Wei, Zebin;Zhang, Jun
关键词：Sulfaquinoxaline (SQ); Bacillus sp. strain DLY-11; Response surface methodology; Degradation condition optimization; Degradation mechanisms
-
Digestate-based organic amendment substitution improves the red soil quality and pakchoi yield
作者：Zhen, Feng;Xing, Tao;Zhang, Yifan;Zhou, Hengbing;Peng, Xuya;Li, Lei;Zhen, Feng;Xing, Tao;Zhang, Hongqiong;Pang, Yuwan
关键词：Red soil; Digestate-based organic amendment; Soil quality index; Pakchoi yield; Microbial communities
-
Insight into the mechanisms of methane production enhancement by bioaugmentation with H2/CO2 in anaerobic digestion
作者：Yang, Jiancheng;Xing, Tao;Sun, Yongming;Li, Lianhua;Li, Ying;Guo, Ying;Zhen, Feng;Pang, Yuwan;Xing, Tao;Sun, Yongming;Li, Lianhua;Li, Ying;Guo, Ying;Zhen, Feng;Yang, Jiancheng;Qu, Bin;Yang, Haojun
关键词：Hydrogenotrophic methanogens; Molar ratios; Domestication; Microbial community
-
Enhanced biodegradation of sulfamethazine in swine manure composting: Pathway elucidation, mechanism insights, and optimization of a novel Bacillus sp. strain
作者：Lin, Xiaojun;Luo, Zifeng;Tu, Hongxing;Wang, Xiujuan;Cai, Qianyi;Zeng, Jingwen;Qiu, Jinrong;Lin, Xiaojun;Luo, Zifeng;Tu, Hongxing;Wang, Xiujuan;Cai, Qianyi;Zeng, Jingwen;Qiu, Jinrong;Lin, Xiaojun;Wei, Zebin;Pang, Yuwan;Huang, Jianfeng;Chen, Chunyan;Li, Jingtong
关键词：Swine manure compost; Sulfamethazine (SMZ); High degradation strain; Optimize degradation conditions; Biodegradation pathway
-
Mapping the heterogeneous removal landscape of wastewater virome in effluents of different advanced wastewater treatment systems of swine farm
作者：Xing, Jiabao;Gao, Han;Liu, Guangyu;Cao, Xinyu;Zhong, Jianhao;Xu, Sijia;Li, Yue;Zhang, Guihong;Sun, Yankuo;Zhang, Guihong;Sun, Yankuo;Pang, Yuwan
关键词：Wastewater surveillance; Aquaculture sewage; Virome; Meta-transcriptomics; Virus ecology
-
Effects of biochar combined with MgO desulfurization waste residue on nitrogen conversion and odor emission in chicken manure composting
作者：Pang, Yuwan;Huang, Jianfeng;Pang, Yuwan;Wang, Dehan;Luo, Zifeng;Pang, Yuwan;Huang, Jianfeng;Pang, Yuwan;Huang, Jianfeng;Zhen, Feng;Zhang, Yanli;Huang, Jianfeng
关键词：Chicken manure compost; biochar; MgO desulfurization waste residue; nitrogen conversion; deodorization
