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A Convenient Synthesis of D,L-Selenomethionine

文献类型： 外文期刊

作者： Ran, X. G. 1 ; Cao, D. R. 1 ; Wang, L. Y. 1 ; Lin, Y. C. 2 ;

作者机构： 1.S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Guangdong, Peoples R China

2.Guangdong Acad Agr Sci, Inst Anim Sci, Guangzhou 510640, Guangdong, Peoples R China

关键词： amino acids;alpha-bromo-gamma-butyrolactone;heterocycles;selenium;reduction

期刊名称：POLISH JOURNAL OF CHEMISTRY （ 影响因子：0.393； 五年影响因子：0.38 ）

ISSN：

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收录情况： SCI

摘要： A convenient synthesis of D,L-selenomethionine from alpha-bromo-gamma-butyrolactone in 4 steps and 26% overall yield has been described.Selenomethionine,an unnatural amino acid,has got increasing importance because it has been expected to be a reagent protecting human systems against oxidation,radiations,cancer,aging and related diseases,and is also a source of selenium in the diets of both animals and humans [1].Numerous synthetic methods leading to selenomethionine have been reported [2-9].

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