A unique role of the pyrimidine de novo synthesis enzyme ODCase in Lysobacter enzymogenes
文献类型： 外文期刊
作者： Yang, Mingming 1 ; Tan, Yunxiao 2 ; Ma, Jiabing 2 ; Zhao, Yingjia 3 ; Yan, Xia 4 ; Wang, Nana 3 ; Wang, Pingping 5 ; Tan, Jiaqi 5 ; Ai, Suilong 5 ; Liang, Xiaofei 2 ; Chang, Bangshuai 3 ; Yousif, Obadah E. A. 3 ; Zhao, Chao 2 ; Wang, Bo 6 ; Qian, Guoliang 7 ; Huang, Lili 1 ;
作者机构： 1.Northwest A&F Univ, State Key Lab Crop Stress Resistance & High Effici, Yangling 712100, Peoples R China
2.Northwest A&F Univ, Coll Plant Protect, Yangling 712100, Peoples R China
3.Northwest A&F Univ, Coll Life Sci, Yangling 712100, Peoples R China
4.Northwest A&F Univ, Coll Nat Resources & Environm, Yangling 712100, Peoples R China
5.China Natl Tobacco Corp, Shaanxi Prov Tobacco Corp, Xian 710061, Peoples R China
6.Jiangsu Acad Agr Sci, Inst Plant Protect, Nanjing 210014, Peoples R China
7.Nanjing Agr Univ, Coll Plant Protect, Lab Plant Immun, Nanjing 210095, Peoples R China
关键词： ODCase; pyrimidine de novo synthesis; secondary metabolite HSAF; Lysobacter enzymogenes
期刊名称：JOURNAL OF INTEGRATIVE AGRICULTURE （ 影响因子：4.4； 五年影响因子：4.8 ）
ISSN： 2095-3119
年卷期： 2024 年 23 卷 9 期
页码：
收录情况： SCI
摘要：
Bacterial species of the genus Lysobacter are environmentally ubiquitous with strong antifungal biocontrol potential. Heat-stable antifungal factor (HSAF) secreted by the biocontrol bacterium Lysobacter enzymogenes OH11 has broad-spectrum and highly efficient antifungal activity. Studying the biosynthetic regulations of HSAF would lay an important foundation for strain engineering toward improved HSAF production. In this work, we demonstrate that Le0752, an orotidine-5
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