Unveiling the role of bZIP transcription factors CREB and CEBP in detoxification metabolism of Nilaparvata lugens (Stal)
文献类型： 外文期刊
作者： Jin, Ruoheng 1 ; He, Biyan 2 ; Qin, Yao 2 ; Du, Zuyi 2 ; Cao, Chunxia 1 ; Li, Jianhong 2 ;
作者机构： 1.Hubei Acad Agr Sci, Natl Biopesticide Engn Res Ctr, Hubei Biopesticide Engn Res Ctr, Wuhan 430064, Peoples R China
2.Huazhong Agr Univ, Coll Plant Sci & Technol, Hubei Insect Resources Utilizat & Sustainable Pest, Wuhan 430070, Peoples R China
3.Tongling Municipal Bur Agr & Rural Affairs, Tongling 244002, Peoples R China
关键词： Brown planthopper; CREB; CEBP; Transcriptional regulation; Detoxification metabolism
期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：8.2； 五年影响因子：7.8 ）
ISSN： 0141-8130
年卷期： 2023 年 253 卷
页码：
收录情况： SCI
摘要： The basic leucine zipper (bZIP) superfamily is a crucial group of xenobiotics in insects. However, little is known about the function of CAAT enhancer binding proteins (CEBP) and cAMP response element binding protein (CREB) in Nilaparvata lugens. In the present study, NlCEBP and NlCREB were cloned and identified. Quantitative polymerase real-time chain reaction (qRT-PCR) analysis showed the expression of NlCEBP and NlCREB was significantly induced after chemical insecticides exposure. Silencing of NlCEBP and NlCREB increased the sus-ceptibility of N. lugens to insecticides, and the detoxification enzyme activities were also significantly decreased. In addition, comparative transcriptome analysis revealed that 174 genes were significantly co-down-regulated after interfering with the two transcription factors. GO analysis showed that co-down-regulated genes are mostly related to energy transport and metabolic functions indicating the potential regulatory role of NlCEBP and NlCREB in detoxification metabolism. Our research shed lights on the functional roles of transcription factors NlCEBP and NlCREB in the detoxification metabolism of N. lugens, providing a theoretical basis for pest management and comprehensive control of this pest and increasing our understanding of insect toxicology.
- 相关文献
作者其他论文 更多>>
-
An ultra-lightweight efficient network for image-based plant disease and pest infection detection
作者：Wang, Beibei;Cao, Chunxia;Huang, Daye;Gong, Yan;Zhang, Chenxiao;Li, Yanyan
关键词：Plant disease detection; Pest infection detection; Convolutional neural network; Deep learning
-
Carboline derivatives based on natural pityriacitrin as potential antifungal agents
作者：Huang, Daye;Zhang, Zhigang;Liu, Fang;Huang, Wenbo;Min, Yong;Wang, Kaimei;Yang, Jingzhong;Cao, Chunxia;Gong, Yan;Ke, Shaoyong;Huang, Daye;Zhang, Zhigang;Liu, Fang;Huang, Wenbo;Min, Yong;Wang, Kaimei;Yang, Jingzhong;Cao, Chunxia;Gong, Yan;Ke, Shaoyong;Li, Yanyan
关键词：Carboline alkaloids; Carboline derivatives; Antifungal activity; Broad-spectrum
-
Efficacy of an adhesive nanopesticide on insect pests of rice in field trials
作者：Gao, Yunhao;Li, Donglin;Xu, Pengfei;Mao, Kaikai;Zhang, Yunhua;Qin, Xueying;Wan, Hu;Li, Jianhong;He, Shun;Li, Dongyang;Tang, Tao;Guo, Mingcheng
关键词：Nanopesticide; Cnaphalocrocis medinalis (Guenee); Chilo suppressalis (Walker); Field trial; Biosafety
-
Sulfur-containing natural hinduchelins derivatives as potential antifungal agents against Rhizoctonia solani
作者：Ke, Shaoyong;Fang, Wei;Huang, Wenbo;Zhang, Zhigang;Shi, Liqiao;Wan, Zhongyi;Wang, Kaimei;Cao, Chunxia;Huang, Daye
关键词：Hinduchelins derivatives; Sulfur-containing derivatives; Natural products; Antifungal activity
-
Synthesis and Antifungal Activity of Substituted 2-Aryl Benzimidazoles Derivatives
作者：Huang, Daye;Qiu, Fang;Zhang, Zhigang;Shi, Liqiao;Cao, Chunxia;Ke, Shaoyong
关键词：
-
Antibiotics increased host insecticide susceptibility via collapsed bacterial symbionts reducing detoxification metabolism in the brown planthopper, Nilaparvata lugens
作者：Tang, Tao;Zhang, Yunhua;Cai, Tingwei;Deng, Xiaoqian;Liu, Chaoya;Li, Jingmin;He, Shun;Li, Jianhong;Wan, Hu;Tang, Tao
关键词：Bacterial symbionts; Detoxification metabolism; Nilaparvata lugens; P450s; Gsts
