Structurally Various Sorbicillinoids From an Endophytic Fungus Acremonium citrinum SS-g13
文献类型： 外文期刊
作者： Peng, Xiao-Ping 1 ; Li, Gang 1 ; Wang, Li-Mei 1 ; Wang, Qi 1 ; Wang, Cong 2 ; Ji, Li-Xia 1 ; Cao, Chen-Xi 1 ; Lin, Guo-Feng 1 ; Jiang, Zu-Yang 1 ; He, Zhuo-qian 1 ; Wang, Pei 3 ; Lou, Hong-Xiang 1 ;
作者机构： 1.Qingdao Univ, Sch Pharm, Dept Nat Med Chem & Pharmacognosy, Qingdao, Peoples R China
2.Guangxi Univ Nationalities, Guangxi Key Lab Chem & Engn Forest Prod, Nanning, Peoples R China
3.Chinese Acad Trop Agr Sci, Hainan Inst Trop Agr Resources, Inst Trop Biosci & Biotechnol, Hainan Key Lab & Dev Nat Prod Li Folk Med, Haikou, Hainan, Peoples R China
4.Shandong Univ, Sch Pharmaceut Sci, Dept Nat Prod Chem, Key Lab Chem Biol,Minist Educ, Jinan, Peoples R China
关键词： sorbicillinoid; trisorbicillinoid; Acremonium; endophyte; Fructus mori
期刊名称：FRONTIERS IN MICROBIOLOGY （ 影响因子：6.064； 五年影响因子：6.843 ）
ISSN：
年卷期： 2022 年 13 卷
页码：
收录情况： SCI
摘要： Three new sorbicillinoids, including trimer trisorbicillinone E (1), acremosorbicillinoids A and B (2 and 3), and a new alkaloid acremokaloid A (4), and a new natural product 2S,3S-acetyl-beta-methyltryptophan (5), were isolated from an endophytic fungus Acremonium citrinum SS-g13, which is found in Fructus mori plant root. In addition, eight known sorbicillinoids (6-13) were also obtained. The new compound structures were established using NMR, HRESIMS spectra, and reported spectroscopic data. The absolute configurations of compounds 1-5, were determined by spectroscopic analysis, Snatzke's method, and time-dependent density functional theory-electronic circular dichroism (TDDFT-ECD) calculations. Compound 11 exhibited significant cholesterol efflux enhancing activity. A plausible biosynthesis pathway for the sorbicillinoids is discussed.
- 相关文献
作者其他论文 更多>>
-
Leveraging a phased pangenome for haplotype design of hybrid potato
作者：Cheng, Lin;Wang, Nan;Bao, Zhigui;Yang, Yuting;Wang, Pei;Zhang, Zhiyang;Tang, Die;Zhang, Pingxian;Wu, Yaoyao;Zhou, Yao;Zheng, Yi;Hu, Yong;Lian, Qun;Ma, Zhaoxu;Zhang, Chunzhi;Zhou, Yongfeng;Huang, Sanwen;Cheng, Lin;Lassois, Ludivine;Wang, Nan;Zhou, Yongfeng;Huang, Sanwen;Bao, Zhigui;Zhou, Qian;Guarracino, Andrea;Garrison, Erik;Tang, Die;Wu, Yaoyao;Zhou, Yao;Lucas, William J.;Stein, Nils;Stein, Nils;Staedler, Thomas;Staedler, Thomas
关键词：
-
The impact of agricultural land use on the linkages between soil microbial communities and agroecosystem functioning is depth-dependent
作者：Cao, Wenchao;Zou, Yukun;Shan, Ying;Wang, Jinchuang;Li, Gang;Singh, Brajesh Kumar;Singh, Brajesh Kumar
关键词：Deep soil; Soil organic carbon; C mineralization; Net N mineralization; Soil microorganisms; Extracellular enzyme activities
-
Artemisinin supplementation in concentrated cottonseed protein basal diets enhances growth, antioxidant capacity, intestinal immunity and microbiota in hybrid grouper (Epinephelus fuscoguttatus p x E. lanceolatus ♂)
作者：Pan, Ling;Wang, Yan;Wang, Qi;Dong, Xiaohui;Xie, Shiwei;Tan, Beiping;Liu, Hongyu;Li, Weikang;Wang, Yan
关键词：Plant protein; Chinese herbal medicine; Artemisia annua; Intestinal microbiota; Immune response
-
Nauclofficines A and B, two novel monoterpenoid indole alkaloids from the Li folk herb Nauclea officinalis with anti-allergic inflammatory effects on RBL-2H3 cells
作者：Li, Yan-li;Wang, Ting;Wang, Hao;Wang, Qi;Cai, Cai-Hong;Mei, Wen-Li;Dai, Hao-Fu;Huang, Sheng-Zhuo;Dai, Hao-Fu;Huang, Sheng-Zhuo;Li, Yan-li;Xu, Feng-Qing;Wang, Ting;Zhu, Guo-Peng
关键词：Nauclea officinalis; Monoterpenoid indole alkaloid; Li folk medicine; Anti-inflammatory activity; Nauclofficine
-
Fatty Acid and Lipid Metabolism in Oil Palm: From Biochemistry to Molecular Mechanisms
作者：Afifi, Eman H.;Martin, Jerome Jeyakumar John;Wang, Qi;Li, Xinyu;Liu, Xiaoyu;Zhou, Lixia;Li, Rui;Fu, Dengqiang;Li, Qihong;Ye, Jianqiu;Cao, Hongxing;Afifi, Eman H.;Martin, Jerome Jeyakumar John;Wang, Qi;Li, Xinyu;Liu, Xiaoyu;Zhou, Lixia;Li, Rui;Fu, Dengqiang;Li, Qihong;Ye, Jianqiu;Cao, Hongxing;Afifi, Eman H.
关键词：oil palm; fatty acid metabolism; lipid biosynthesis; lipid accumulation; biochemical pathways; molecular mechanisms
-
Comprehensive metabolite profiling reveals biochemical evolution in coconut water during fruit development
作者：Hou, Mingming;Martin, Jerome Jeyakumar John;Dong, Zhiguo;Wang, Qi;Chen, Yongxiu;Song, Yuqiao;Sun, Chengxu;Cao, Hongxing;Hou, Mingming;Li, Wenrao;Chen, Yongxiu;Song, Yuqiao;Martin, Jerome Jeyakumar John;Dong, Zhiguo;Sun, Chengxu;Cao, Hongxing;Wang, Qi
关键词：Hainan wenchang sweet coconut; Secondary metabolites; Liquid chromatography tandem mass spectrometry; Metabolomics; nutrient substance
-
Diaporchalasins A-E, New Cytochalasins from the Endophytic Fungus Diaporthe sp. BMX12 Isolated from Aquilaria sinensis
作者：Yang, Li;Wang, Qi;Ma, Qing-Yun;Xie, Qing-Yi;Gai, Cui-Juan;Dai, Hao-Fu;Zhao, You-Xing;Yang, Li;Wang, Qi;Ma, Qing-Yun;Xie, Qing-Yi;Gai, Cui-Juan;Dai, Hao-Fu;Zhao, You-Xing;Wu, You-Gen
关键词：Diaporthe sp.; Endophytic fungus; Cytochalasin; Cytotoxicity
