Statistical Analysis of Reproductive Traits in Jinwu Pig and Identification of Genome-Wide Association Loci
文献类型： 外文期刊
作者： Chen, Wenduo 1 ; Zhao, Ayong 1 ; Pan, Jianzhi 3 ; Tan, Kai 3 ; Zhu, Zhiwei 3 ; Zhang, Liang 3 ; Yu, Fuxian 3 ; Liu, Renhu 3 ; Zhong, Liepeng 4 ; Huang, Jing 3 ;
作者机构： 1.Zhejiang A&F Univ, Coll Anim Sci & Technol, Hangzhou 311300, Peoples R China
2.Zhejiang A&F Univ, Coll Vet Med, Hangzhou 311300, Peoples R China
3.Zhejiang Acad Agr Sci, Inst Virol & Biotechnol, Hangzhou 310021, Peoples R China
4.Fujian Agr & Forestry Univ, Coll Anim Sci, Fuzhou 350002, Peoples R China
关键词： reproductive traits; genome-wide association analysis; Jinwu pig; SNPs
期刊名称：GENES （ 影响因子：2.8； 五年影响因子：3.2 ）
ISSN：
年卷期： 2025 年 16 卷 5 期
页码：
收录情况： SCI
摘要： Background: The Jinwu pig is a novel breed created by crossbreeding Jinhua and Duroc pigs, displaying superior meat quality, strong adaptability to coarse feed, high production performance, and a rapid growth rate. However, research on its reproductive traits and genomic characteristics has not been systematically reported. Methods: In this study, we investigated the genetic basis of reproductive traits in Jinwu pigs us-ing a genome-wide association study. We analyzed 2831 breeding records from 516 Jinwu sows to evaluate the effects of fixed factors (farrowing season, parity, and mated boar) on six reproductive traits: the total number of births (TNB), number born alive (NBA), number of healthy offspring produced (NHOP), weak litter size (WLS), number of stillbirths (NS), and number of mummies (NM). Results: A total of 771 genome-wide significant single-nucleotide polymorphisms (SNPs) and ten potential candidate genes associated with pig reproductive traits were identified: VOPP1, PGAM2, TNS3, LRFN5, ORC1, CC2D1B, ZFYYE9, TUT4, DCN, and FEZF1. TT-genotype-carrier individuals of the pleiotropic SNP rs326174997 exhibited significantly higher TNB, NBA, and NHOP trait-related phenotypic values. Conclusions: These findings provide a foundation for the reproductive breeding of Jinwu pigs and offer new insights into molecular genetic breeding in pigs.
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