Transcriptome analysis of response mechanism to Microcystin-LR and microplastics stress in Asian clam (Corbicula fluminea)
文献类型： 外文期刊
作者： Zhang, Jiahua 1 ; Jie, Wang 1 ; Cheng, Guofeng 1 ; Liu, Xingguo 1 ;
作者机构： 1.Chinese Acad Fishery Sci, Fishery Machinery & Instrument Res Inst, Shanghai 200092, Peoples R China
2.Minist Agr & Rural Affairs, Key Lab Aguaculture Facil Engn, Shanghai, Peoples R China
关键词： Microcystin-LR; Microplastics; Combined toxicities; Asian clam; Transcriptomics
期刊名称：FISH & SHELLFISH IMMUNOLOGY （ 影响因子：4.7； 五年影响因子：4.7 ）
ISSN： 1050-4648
年卷期： 2023 年 139 卷
页码：
收录情况： SCI
摘要： In this study, we analyzed the hepatopancreas tissues of Asian Clam (Corbicula fluminea) exposed to three different adverse environmental conditions from the same batch using RNA-seq. The four treatment groups included the Asian Clam group treated with Microcystin-LR (MC), the Microplastics-treated group (MP), the Microcystin-LR and Microplastics-treated group (MP-MC), and the Control group. Our Gene Ontology analysis revealed 19,173 enriched genes, and the Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis identified 345 related pathways. The KEGG pathway analysis demonstrated that the MC vs control group and the MP vs control group were significantly enriched in immune and catabolic pathways such as Antigen processing and presentation, Rheumatoid arthritis, Lysosome pathway, Phagosome pathway, and Autophagy pathway. We also evaluated the effects of Microplastics and Microcystin-LR on the activities of eight antioxidant enzymes and immune enzymes in Asian clams. Our study enriched the genetic resources of Asian clams and provided valuable information for understanding the response mechanism of Asian clams to microplastics and microcystin in the environment, through the identification of differentially expressed genes and related pathway analyses from the large number of transcriptome sequences obtained.
- 相关文献
作者其他论文 更多>>
-
Hydrodynamics of waste collection in a recirculating aquaculture tank with different flow-guide discs
作者：Zhang, Jun;Zhang, Ning;Wang, Minghua;Chen, Congcong;Gao, Yang;Cao, Shouqi;Hu, Qinsong;Zhang, Zheng;Zhang, Jun;Liu, Xingguo
关键词：Recirculating aquaculture system; Hydraulic characteristics; Particle removal efficiency; Self-cleaning performance
-
Effects of polystyrene nanoplastics on hormonal regulation and glucose metabolism of Pacific whiteleg shrimp (Litopenaeus vannamei)
作者：Li, Yiming;Liu, Xingguo;Wang, Xiaodong;Che, Xuan;Zhu, Bihong;Zhu, Xiaoyi;Ye, Yucong;Zhao, Yunlong
关键词：
-
Colonial Microcystis' biomass affects its shift to diatom aggregates under aeration mixing
作者：Wang, Xiaodong;Che, Xuan;Liu, Ziqiu;Liu, Xingguo;Zhou, Jian;Qin, Boqiang;Tang, Xiangming
关键词：Cyanobacteria blooms; Microcystis colonies; Hydrodynamic disturbance; Nitzschia aggregates; Nutrients; Low light
-
Transcriptome Analysis of Different Aquaculture Substrates on the Immune Response of Babylonia areolata
作者：Zhang, Jiahua;Wang, Jie;Gu, Zhaojun;Liu, Xingguo;Zhang, Jiahua;Wang, Jie;Gu, Zhaojun;Liu, Xingguo
关键词：Babylonia areolate; Substrates; Recirculating aquaculture systems; Immune response; Transcriptome
-
Degradation performance and mechanism of microcystins in aquaculture water using low-temperature plasma technology
作者：Zhang, Jiahua;Liu, Xingguo;Zhang, Jiahua;Liu, Xingguo;Shangguan, Yuyi;Wang, Jie;Zhang, Jiahua;Shangguan, Yuyi;Yang, Guanyi;Liu, Xingguo
关键词：Plasma; Advancedoxidation processes; Microcystin-LR; Cytotoxicity; Algal blooms
-
Exposure to polystyrene nanoplastics induces apoptosis, autophagy, histopathological damage, and intestinal microbiota dysbiosis of the Pacific whiteleg shrimp (Litopenaeus vannamei)
作者：Li, Yiming;Liu, Xingguo;Che, Xuan;Yuan, Haojuan;Rihan, Na;Zhao, Yunlong;Zhu, Tian
关键词：Nanoplastics; Litopenaeus vannamei; Immunity; Gut microbiota; Apoptosis
-
Polystyrene nanoplastics exposure alters muscle amino acid composition and nutritional quality of Pacific whiteleg shrimp (Litopenaeus vannamei)
作者：Li, Yiming;Liu, Xingguo;Che, Xuan;Ye, Yucong;Rihan, Na;Zhu, Bihong;Zhao, Yunlong;Jiang, Qichen
关键词：Nanoplastic; Litopenaeus vannamei; Histological change; Gene expression
