Dendrobium officinale polysaccharides: alleviating UVB-induced skin damage by anti-oxidation and inhibiting matrix metalloproteinases expression
文献类型： 外文期刊
作者： Xu, Zhejie 1 ; Zhou, Wanyi 2 ; Yang, Chenchen 2 ; Zhang, Ni 2 ; Li, Jingrui 2 ; Tao, Wenyang 2 ; Xing, Jianrong 2 ; Yang, Ying 2 ; Dang, Yali 1 ;
作者机构： 1.Ningbo Univ, Coll Food Sci & Engn, Ningbo 315211, Zhejiang, Peoples R China
2.Zhejiang Acad Agr Sci, Inst Food Sci, Hangzhou 310021, Zhejiang, Peoples R China
关键词：
期刊名称：FOOD SCIENCE AND BIOTECHNOLOGY （ 影响因子：3.1； 五年影响因子：3.5 ）
ISSN： 1226-7708
年卷期： 2025 年 34 卷 10 期
页码：
收录情况： SCI
摘要： Ultraviolet B (UVB) is a major external factor causing ultraviolet damage. This study assessed the protective effects of Dendrobium officinale polysaccharides (DOP) from both stems and leaves on UVB-induced skin damage in HaCaT Human Keratinocytes. Notably, stem DOPs (DOP1J, DOP3J, and DOP8J) outperformed leaf DOPs (DOP1Y, DOP3Y, and DOP8Y) in mitigating UVB-induced damage, with DOP1J and DOP8J demonstrating the highest efficacy in preserving cell proliferation. The DOPs exhibited antioxidant properties by enhancing superoxide dismutase, catalase, and glutathione peroxidase activities, and reducing reactive oxygen species levels. They curtailed cellular aging by inhibiting UVB-induced protein phosphorylation of p38, JNK, and ERK1/2 within the mitogen-activated protein kinase (MAPK) signaling pathway and by suppressing the protein expression of p53 and matrix metalloproteinases (MMPs, including MMP-1 and MMP-9). The mechanism underlying DOPs' protective effects appears to be a dual-action approach: bolstering antioxidant defenses and dampening the MAPK pathway's activation, thereby hindering the expression of MMPs.
- 相关文献
作者其他论文 更多>>
-
Insight into the enhancement and mechanism of saltiness perception by salty peptides from bovine bone
作者：Wang, Haiyan;Lu, Wenjing;Chen, Di;Chen, Xuan;Zhang, Cen;Xiao, Chaogeng;Wang, Haiyan;Xiao, Chaogeng;Dang, Yali;Chen, Xuan;Gou, Zhongjun;Wang, Yongjun
关键词：Salty peptides; TMC4; Sodium reduction; Stevens' law; Molecular dynamics simulation
-
Effect of soybean phosphatidylethanolamine-tamarind gum Maillard conjugate on physicochemical stability of water-in-oil emulsions
作者：Wang, Mengzhu;Yang, Ying;Xing, Jianrong;Zhou, Wanyi;Tao, Wenyang;Fan, Liuping;Li, Jinwei
关键词：W/O emulsion; Soybean phosphatidylethanolamine-tamarind; gum-Maillard conjugate; Physicochemical stability
-
Sodium alginate as a stabilizer for anthocyanins in Dendrobium officinale: Insights from experimental approach and molecular dynamics
作者：Tao, Wenyang;Yang, Chenchen;Wang, Mengzhu;Li, Jingrui;Zhou, Wanyi;Xing, Jianrong;Yang, Ying;Yang, Chenchen;Li, Ming;Zhao, Yuping
关键词：Dendrobium Officinale anthocyanins; Sodium alginate; Thermal stability; Molecular simulation
-
Dendrobium officinale leaf polysaccharide has a dual effect of alleviating the syndromes of immunosuppressed mice and modulating immune system of normal mice
作者：Li, Jingrui;Tao, Wenyang;Zhou, Wanyi;Xing, Jianrong;Luo, Mengfan;Lu, Shengmin;Yang, Ying
关键词：Dendrobium officinale leaf; Polysaccharide; Immune system; Gut microbiota; Cyclophosphamide
-
Effects of Dityrosine on Lactic Acid Metabolism in Mice Gastrocnemius Muscle During Endurance Exercise via the Oxidative Stress-Induced Mitochondria Damage
作者：Xia, Qiudong;Lan, Jinchi;Pan, Yuxiang;Wang, Yuxin;Song, Tianyuan;Gu, Zhenyu;Ding, Yin-Yi;Yang, Ying;Tian, Xu;Chen, Longjun
关键词：dityrosine; lactate acid metabolism; enduranceexercise; oxidative stress; mitochondria damage
-
Novel salty peptides derived from bovine bone: Identification, taste characteristic, and salt-enhancing mechanism
作者：Wang, Haiyan;Xiao, Chaogeng;Chen, Di;Lu, Wenjing;Zhang, Cen;Xiao, Chaogeng;Dang, Yali;Liu, Zhenmiao;Chen, Guangyin;Wang, Bin
关键词：Bovine bone; Salty peptides; Sodium reduction; Molecular docking
-
Differential impacts of porous starch versus its octenyl succinic anhydride-modified counterpart on naringin encapsulation, solubilization, and in vitro release
作者：Wang, Lu;Lu, Shengmin;Liu, Yinying;Lu, Hanyu;Zheng, Meiyu;Zhou, Zhongjing;Cao, Feng;Yang, Ying;Liu, Yinying;Lu, Hanyu;Fang, Zhongxiang
关键词：Modified starches; Naringin encapsulation and solubilization; In vitro release
