您好，欢迎访问黑龙江省农业科学院 机构知识库！
黑龙江省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Transcriptome Analysis Reveals Genes Contributed to Min Pig Villi Hair Follicle in Different Seasons

文献类型： 外文期刊

作者： Tian, Ming 1 ; He, Xinmiao 1 ; Wang, Wentao 1 ; Feng, Yanzhong 1 ; Zhang, Dongjie 1 ; Li, Zhongqiu 1 ; Liu, Di 1 ;

作者机构： 1.Heilongjiang Acad Agr Sci, Inst Anim Husb, Harbin 150086, Peoples R China

关键词： Min pig; villi hair follicle; season

期刊名称：VETERINARY SCIENCES （ 影响因子：2.518； ）

ISSN：

年卷期： 2022 年 9 卷 11 期

页码：

收录情况： SCI

摘要： Simple Summary In this research, we described the phenotype of Min pig dermal villi and sequenced the mRNA transcriptome of Min pig hair follicles. The results showed that the hair growth in Min pigs was regulated by an interaction network composed of eight core genes. The Min pig, a local pig breed in China, has a special trait which has intermittent villus and coat hair regeneration. However, the regulation and mechanism of villus in Min pigs have not yet been described. We observed and described the phenotype of Min pig dermal villi in detail and sequenced the mRNA transcriptome of Min pig hair follicles. A total of 1520 differentially expressed genes (DEG) were obtained.K-means hierarchical clustering showed that there was a significant expression pattern difference in winter compared with summer. Gene enrichment and network analysis results showed that the hair growth in Min pigs was closely related to the composition of desmosomes and regulated by an interaction network composed of eight core genes, namely DSP, DSC3, DSG4, PKP1, TGM1, KRT4, KRT15, and KRT84. Methylation analysis of promoters of target genes showed that the PKP1 gene was demethylated. Our study will help to supplement current knowledge of the growth mechanism of different types of hair.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：黑龙江省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台