Expression pattern of L-FABP gene in different tissues and its regulation of fat metabolism-related genes in duck
文献类型: 外文期刊
作者: He, Jun 1 ; Tian, Yong 1 ; Li, Jinjun 1 ; Shen, Junda 1 ; Tao, Zhengrong 1 ; Fu, Yan 2 ; Niu, Dong 2 ; Lu, Lizhi 1 ;
作者机构: 1.Zhejiang Acad Agr Sci, Inst Anim Husb & Vet Sci, Hangzhou 310021, Zhejiang, Peoples R China
2.Zhejiang Univ, Coll Anim Sci, Hangzhou 310058, Zhejiang, Peoples R China
关键词: Duck;L-FABP;SiRNA;Fat metabolism-related gene;Oleic acid
期刊名称:MOLECULAR BIOLOGY REPORTS ( 影响因子:2.316; 五年影响因子:2.357 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: Liver fatty acid binding protein (L-FABP) is a member of intracellular lipid-binding proteins responsible for the transportation of fatty acids. The expression pattern of duck L-FABP mRNA was examined in this study by quantitative RT-PCR. The resultsshowed that duck L-FABP gene was expressed in many tissues, including heart, lung, kidney, muscle, ovary, brain, intestine, stomach and adipocyte tissues, and highly expressed in liver. Several lipid metabolism-related genes were selected to detect the regulation of L-FABP in duck. The expression of L-FABP and lipoprotein lipase was promoted by oleic acid. The L-FABP knockdown decreased the expression levels of peroxisome proliferator-activated receptor alpha (PPAR alpha), fatty acid synthase and lipoprotein lipase by 61.1, 42.3 and 53.7 %, respectively (P < 0.05), but had no influences on the mRNA levels of PPAR gamma and leptin receptor. L-FABP might function through the PPAR alpha to regulate the fat metabolism-related gene expression and play important roles in lipid metabolism in duck hepatocytes.
- 相关文献
作者其他论文 更多>>
-
Advancements in understanding and improving duck egg odor: Mechanisms, influential factors, and innovative strategies
作者:Dong, Qishan;Sun, Yangying;Pan, Daodong;He, Jun;Dong, Qishan;Lu, Lizhi;Tian, Yong;Zeng, Tao
关键词:Duck egg; Odor formation; Trimethylamine; Gut microbiota; Reducing odor; Coating preservation
-
In vitro modeling of feline gut fermentation: a comprehensive analysis of fecal microbiota and metabolic activity
作者:Ren, Qianle;Li, Yuling;Duan, Mingmei;Li, Jinjun;Shi, Fangshu;Li, Xiaoqiong;Ren, Qianle;Li, Yuling;Duan, Mingmei;Li, Jinjun;Shi, Fangshu;Li, Xiaoqiong;Ren, Qianle;Zhou, Yun;Hu, Wanjing;Mao, Junfu
关键词:cat; gut microbiota;
in vitro fermentation; targeted metabolites; SCFAs -
D-mannose-modified nanoliposomes enhance the targeted delivery of ovalbumin to improve its anti-inflammatory, antioxidant, and macrophage polarization effects
作者:Liao, Jiahao;Chi, Xiaoyi;Wang, Weiwei;Huang, Jianyu;Li, Xiaoqiong;Kuang, Jian;Li, Jianqiang;Bian, Xiangyu;Li, Jinjun;Pang, Jinzhu;Wang, Weiwei
关键词:D-mannose nanoliposome; Ovalbumin delivery; Macrophage targeting; Anti-inflammatory effects
-
Influence of fermented feed on lipid composition and volatile flavor profile of duck eggs: Insights from multi-omics analysis
作者:Dong, Qishan;Lu, Lizhi;Gu, Tiantian;Tian, Yong;Zong, Yibo;Zeng, Tao;Dong, Qishan;He, Jun;Lu, Lizhi;Gu, Tiantian;Tian, Yong;Zong, Yibo;Zeng, Tao;Sun, Jing;Huang, Yu;Fu, Qiuling
关键词:Volatile flavor; Duck eggs; Lipidomics; Fermented feed; Off-odor
-
Polystyrene microplastics exacerbate mitophagy through mitochondrial dysfunction in the duck lung
作者:Gu, Tiantian;Duan, Mingcai;Chen, Li;Tian, Yong;Xu, Wenwu;Zeng, Tao;Lu, Lizhi;Kong, Minghua;Lu, Lizhi
关键词:Duck; Polystyrene microplastics; Mitochondrion; TCA cycle; Mitophagy
-
Enhancing Akkermansia growth via phytohormones: a strategy to modulate the gut-bone axis in postmenopausal osteoporosis therapy
作者:Zhao, Zhiqi;Zhu, Liying;Wang, Xin;Li, Xiaoqiong;Li, Jinjun;Zhao, Zhiqi;Zhu, Liying;Wang, Xin;Li, Xiaoqiong;Li, Jinjun;Zhao, Zhiqi;Sun, Haibiao;Han, Xiaoqiang;Deng, Yixuan;Li, Li
关键词:Osteoporosis; Phytohormones; Soybean isoflavone; Naringin; Denosumab; Gut microbiome
-
Comparison of laying performance and egg quality between peak and late laying phases in Korean quail
作者:Ma, Yanfen;Chen, Qi;Hua, Xuanke;Zhang, Xinyun;Zhao, Xinyu;Liu, Xin;Lu, Lizhi
关键词:Quail; Ovary; Eggshell gland; Laying performance; Egg quality



