Evaluation of toxicological impacts on Sprague-Dawley rat by successively low dose of aflatoxin B1
文献类型： 外文期刊
作者： Wei, Wei 1 ; Li, Rui 1 ; He, Liang 2 ; Wang, Xu 1 ; Ji, Xiaofeng 1 ; Zhou, Yu 1 ;
作者机构： 1.Zhejiang Acad Agr Sci, State Key Lab Breeding Base Zhejiang Sustainable, Zhejiang Prov Key Lab Food Safety, Inst Qual & Standard Agroprod, Hangzhou 310021, Zhejiang, Peoples R China
2.Natl Shanghai Ctr New Drug Safety Evaluat & Res, Shanghai Inst Pharmaceut Ind, Shanghai 201203, Peoples R Chi
关键词： aflatoxins;liver function;kidney function;regulatory limits;toxicological impacts
期刊名称：JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE （ 影响因子：3.638； 五年影响因子：3.802 ）
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收录情况： SCI
摘要： BACKGROUND: Aflatoxins (AFs) are a group of potent mycotoxins that frequently pollute agro-products and animal feeds. For complex reasons, the regulatory limits of AFs differ from nation to nation. In this study, feedstuffs contaminated with various concentrations of aflatoxin B1 (AFB1) corresponding to AF regulatory limits of major agro-product importing and exporting nations were tested in Sprague-Dawley rats, and the toxicological results were evaluated.
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