文献类型： 外文期刊
作者： Zhang, Zhong 1 ; Liu, Rui-Na 2 ; Tang, Qing-Jiu 1 ; Zhang, Jing-Song 1 ; Yang, Yan 1 ; Shang, Xiao-Dong 1 ;
作者机构： 1.Shanghai Acad Agr Sci, Inst Edible Fungi, Key Lab Edible Fungi Resources & Utilizat South, Minist Agr,Natl Engn Res Ctr Edible Fungi, Shanghai 201403, Peoples R China
2.Nanjing Agr Univ, Coll Life Sci, Nanjing 210095, Jiangsu, Peoples R China
关键词： Diterpene;Hericium erinaceus;Cytotoxicity;Antibacterial activity
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）
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收录情况： SCI
摘要： One new diterpene (1) and new compound (2), along with four known compounds (3-6) were isolated from the fungal mycelia of Hericium erinaceus by the tracking method of antibacterial activity. The structures of compounds (1-6) were elucidated on the basis of spectral data. Compound (3) showed strong antibacterial activity against Helicobacter pylori (ATCC43504) and compounds (1), (2) and (4) showed moderate antibacterial activity. Compound (1) exhibited good cytotoxicity against three human cancer cell lines (K562, LANCAP, HEP2). (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
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