您好，欢迎访问中国水产科学研究院 机构知识库！
中国水产科学研究院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Distortion of frontal bones results from cell apoptosis by the mechanical force from the up- migrating eye during metamorphosis in Paralichthys olivaceus

文献类型： 外文期刊

作者： Sun, Mingyan 1 ; Wei, Fen 1 ; Li, Hui 1 ; Xu, Juan 1 ; Chen, Xinye 1 ; Gong, Xiaoling 1 ; Tian, Yongsheng 2 ; Chen, Songl 1 ;

作者机构： 1.Shanghai Ocean Univ, Key Lab Explorat & Utilizat Aquat Genet Resources, Minist Educ, Shanghai 201306, Peoples R China

2.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Key Lab Sustainable Dev Marine Fisheries, Minist Agr, Qingdao, Peoples R China

3.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Ins

关键词： Flatfish;Frontal bones;Cell apoptosis;Mechanical force;Eye migration;Metamorphosis

期刊名称：MECHANISMS OF DEVELOPMENT （ 影响因子：1.882； 五年影响因子：2.414 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Craniofacial remodeling during flatfish metamorphosis, including eye migration, is perhaps the most striking example of asymmetric postembryonic development in the vertebrate world. The asymmetry of the cranium mainly results from distortion of the frontal bones, which depends on eye migration during metamorphosis. However, it is unclear how the upmigrating eye causes distortion of the frontal bones. In this study, we first show that distortion of the frontal bones during metamorphosis in Paralichthys olivaceus is the result of cell apoptosis, rather than cell autophagy or cell proliferation. Secondly, we report that cell apoptosis in the frontal bones is induced by the mechanical force transferred from the up-migrating eye. The mechanical force from the up-migrating eye signals through FAK to downstream molecules that are integrated into the BMP-2 signal pathway. Finally, it is shown that cell apoptosis in the frontal bones is activated by the intrinsic mitochondrial pathway; the extrinsic death receptor is not involved in this process. Moreover, cell apoptosis in frontal bones is not induced directly by thyroid hormones, which are thought to mediate metamorphosis in flatfishes and directly mediate cell apoptosis during amphibian metamorphosis. These findings help identify the major signaling route used during regulation of frontal bone distortion during metamorphosis in flatfish, and indicate that the asymmetry of the cranium, or at least the distortion of frontal bones, is the result of rather than the reason underlying eye migration. (C) 2015 Published by Elsevier Ireland Ltd.

  • 相关文献

[1]Biochemical composition of the ovarian fluid and its effects on the fertilization capacity of turbot Scophthalmus maximus during the spawning season. Jia, Y. D.,Meng, Z.,Liu, X. F.,Lei, J. L.,Niu, H. X..

[2]Establishment and characterization of an ovarian cell line from half-smooth tongue sole Cynoglossus semilaevis. Sun, A.,Wang, T. Z.,Wang, N.,Liu, X. F.,Sha, Z. X.,Chen, S. L..

[3]Molecular characterization, sexually dimorphic expression, and functional analysis of 3'-untranslated region of vasa gene in half-smooth tongue sole (Cynoglossus semilaevis). Huang, Jinqiang,Huang, Jinqiang,Lin, Fan.

[4]Molecular cloning and multifunctional characterization of GRIM-19 (gene associated with retinoid-interferon-induced mortality 19) homologue from turbot (Scophthalmus maximus). Wang, Na,Wang, Tianzi,Chen, Songlin,Wang, Xianli,Yang, Changgeng,Zhao, Xiaojie,Zhang, Yuxi.

[5]Molecular cloning, characterization, and expression analysis of a Broad-Complex homolog during development in the oriental river prawn Macrobrachium nipponense. Jiang, S. F.,Sun, S. M.,Gong, Y. S.,Xiong, Y. W.,Qiao, H.,Zhang, W. Y.,Jin, S. B.,Fu, H. T.,Zhang, Y. P.. 2015

[6]First studies of embryonic and larval development of Coilia nasus (Engraulidae) under controlled conditions. Xu, Gangchun,Tang, Xue,Gu, Ruobo,Xu, Pao,Tang, Xue,Le, Guowei,Zhang, Chengxiang,Zheng, Jinliang. 2011

[7]Reproductive performance of one-year-old Pacific abalone (Haliotis discus hannai) and its crossbreeding effect on offspring growth and survival. Li, Jiaqi,Fang, Jianguang,Mao, Yuze,Wang, Mingling,Liu, Xiao,Li, Jiaqi,Wang, Mingling,Liu, Xiao,Mao, Yuze,Fang, Jianguang,Liu, Guangmou,Bian, Dapeng. 2017

[8]Locus Mapping, Molecular Cloning, and Expression Analysis of rps6kb2, a Novel Metamorphosis-Related Gene in Chinese Tongue Sole (Cynoglossus semilaevis). Liu, Yang,Wei, Min,Zhao, Fazhen,Chen, Songlin,Liu, Yang,Wei, Min,Guo, Hua,Shao, Changwei,Meng, Liang,Xu, Wenteng,Wang, Na,Wang, Lei,Cui, Zhongkai,Yang, Yingming,Li, Yangzhen,Zhao, Fazhen,Chen, Songlin,Liu, Yang,Wei, Min,Guo, Hua,Shao, Changwei,Meng, Liang,Xu, Wenteng,Wang, Na,Wang, Lei,Cui, Zhongkai,Yang, Yingming,Li, Yangzhen,Zhao, Fazhen,Chen, Songlin,Guo, Hua,Power, Deborah M.,Cui, Zhongkai,Hou, Jilun,Mahboob, Shahid,Mahboob, Shahid.

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国水产科学研究院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台