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Identification and functional characterization of novel feline cytochrome P450 2A

文献类型: 外文期刊

作者: Okamatsu, Gaku 1 ; Komatsu, Tetsuya 1 ; Kubota, Akira 2 ; Onaga, Takenori 1 ; Uchide, Tsuyoshi 1 ; Endo, Daiji 1 ; Kir 1 ;

作者机构: 1.Rakuno Gakuen Univ, Sch Vet Med, Ebetsu, Hokkaido 0698501, Japan

2.Obihiro Univ Agr & Vet Med, Diagnost Ctr Anim Hlth & Food Safety, Obihiro, Hokkaido 080, Japan

3.Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Wuxi, Peoples R China

4.Shin Nippon Biomed Labs Ltd, Pharmacokinet & Bioanal Ctr, Kainan, Wakayama, Japan

关键词: Carnivore;cytochrome P450;domestic cats;drug metabolism

期刊名称:XENOBIOTICA ( 影响因子:1.908; 五年影响因子:1.917 )

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年卷期:

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收录情况: SCI

摘要: Cytochrome P450s are the major metabolizing enzymes for xenobiotics in humans and other mammals. Although the domestic cat Felis catus, an obligate carnivore, is the most common companion animal, the properties of cytochrome P450 subfamilies are largely unknown.

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