Synthesis and biological activity of novel benzimidazole derivatives as potential antifungal agents
文献类型： 外文期刊
作者： Si, Weijie 1 ; Zhang, Tao 1 ; Li, Yaofa 2 ; She, Dongmei 1 ; Pan, Wenliang 2 ; Gao, Zhanlin 3 ; Ning, Jun 1 ; Mei, Xiangd 1 ;
作者机构： 1.Chinese Acad Agr Sci, Inst Plant Protect, State Key Lab Biol Plant Dis & Insect Pests, Beijing 100193, Peoples R China
2.Minist Agr, Key Lab Integrated Pest Management Crops Northern, Inst Plant Protect, Hebei Acad Agr & Forestry Sci,IPM Ctr Hebei Prov, Baoding 07100, Hebei, Peoples R China
3.Minist Agr, Key Lab Integrated Pest Management Crops Northern, Inst Plant Protec
关键词： benzimidazole derivatives;synthesis;characterization;biological activity;thiabendazole
期刊名称：JOURNAL OF PESTICIDE SCIENCE （ 影响因子：1.519； 五年影响因子：1.596 ）
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收录情况： SCI
摘要： In the present study, a series of novel benzimidazole derivatives containing chrysanthemum acid moieties was designed and synthesized. Preliminary investigation of biological activity indicated that all of the compounds exhibited lower activity than that of beta-cypermethrin against Plutella xylostella and Lipaphis erysimi; meanwhile, they showed good inhibitory activity against Botrytis cinerea and Sclerotinia sclerotiorum in vitro. The fungicidal activity of compound 8a against B. cinerea was approximately equal to that of thiabendazole and was twice as active against S. sclerotiorum as was thiabendazole. In addition, compound 9e displayed the most potent inhibitory activity against both fungi and was almost twice as potent as thiabendazole. (C) Pesticide Science Society of Japan
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