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Damage to the Membrane Permeability and Cell Death of Vibrio parahaemolyticus Caused by Phlorotannins with Low Molecular Weight from Sargassum thunbergii

文献类型: 外文期刊

作者: Wei, Yuxi 1 ; Liu, Qi 2 ; Xu, Chuanjin 3 ; Yu, Jia 1 ; Zhao, Ling 2 ; Guo, Qi 1 ;

作者机构: 1.Qingdao Univ, Coll Life Sci, 308 Ningxia Rd, Qingdao, Peoples R China

2.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao, Peoples R China

3.Qingdao Univ, Coll Med, Affiliated Hosp, 308 Ningxia Rd, Qingdao, Peoples R China

关键词: Sargassum thunbergii;phlorotannin;antibacterial mode;Vibrio parahaemolyticus;membrane permeability

期刊名称:JOURNAL OF AQUATIC FOOD PRODUCT TECHNOLOGY ( 影响因子:1.767; 五年影响因子:1.628 )

ISSN:

年卷期:

页码:

收录情况: SCI

摘要: To understand the mode of action of low molecular weight phlorotannins (LMPs) from Sargassum thunbergii against Vibrio parahaemolyticus, effects of LMPs on the growth curve and the content changes of some substances in culture media were investigated, and those on morphological and ultramicrostructure were also observed by scanning electron microscope and transmission electron microscopy. The results showed that LMPs inhibited thalli growth at logarithmic phase and damaged the cell membrane and cell wall of tested bacteria which led to the leakage of cytoplasm and the deconstruction of membrane permeability. The present study indicates that LMPs as natural products in seaweeds deserve further investigation for food safety control and aquacultural drugs.

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