Anti-adipogenic Effects of Polyphenol Extracts of Areca Flower Tea on 3T3-L1 Preadipocytes
文献类型： 外文期刊
作者： Song, Fei 1 ; Tang, MinMin 1 ; Wu, QiuSheng 2 ; Shen, XiaoJun 1 ; Wang, Hui 1 ; Chen, Hua 1 ; Zhao, SongLin 1 ;
作者机构： 1.Chinese Acad Trop Agr Sci, Coconut Res Inst, Wenchang 571339, Hainan, Peoples R China
2.Huazhong Agr Univ, Coll Food Sci & Technol, Wuhan 430070, Hubei, Peoples R China
关键词： areca flower tea extracts;polyphenol;3T3-L1;adipogenesis;PPAR gamma
期刊名称：FOOD SCIENCE AND TECHNOLOGY RESEARCH （ 影响因子：0.668； 五年影响因子：0.895 ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： This study aimed to investigate the effects of areca flower tea polyphenol extract (AFPE) on the adipogenesis of 3T3-L1 preadipocytes. AFPE was extracted from areca flower tea using boiling water, and the polyphenolic compounds were analysed by HPLC. At doses that they did not induce cytotoxicity, AFPE (50 - 200 mu g/mL) efficiently inhibited triglyceride accumulation in the mature adipocytes in a dose-dependent manner when induced to differentiate. Additionally, AFPE suppressed the secretion of leptin and the expression of lipoprotein lipase (LPL). Moreover, the anti-adipogenic properties were also attributed to the down-regulation of protein expression of major transcriptional factors in adipogenesis, including peroxisome proliferator-activated receptor gamma (PPAR gamma) and CCAT/enhancer-binding protein alpha (C/EBP alpha). Therefore, these results suggest that AFPE may prevent obesity by inhibiting the differentiation of preadipocytes, suggesting its potential application in functional foods and nutraceuticals for obesity management.
- 相关文献
作者其他论文 更多>>
-
Integrated transcriptomic and metabolomic data reveal the cold stress responses molecular mechanisms of two coconut varieties
作者：Li, Jing;Wang, Fangyuan;Sayed, Md. Abu;Shen, Xiaojun;Zhou, Lixia;Liu, Xiaomei;Sun, Xiwei;Chen, Shuangyan;Wu, Yi;Lu, Lilan;Gong, Shufang;Iqbal, Amjad;Yang, Yaodong;Chen, Shuangyan;Iqbal, Amjad
关键词：coconut; varieties; cold stress; transcriptome; metabolome
-
Chemical Components, Nutritional Value, Volatile Organic Compounds and Biological Activities In Vitro of Coconut (Cocos nucifera L.) Water with Different Maturities
作者：Zhang, Yufeng;Kan, Jintao;Liu, Xiaoyan;Song, Fei;Li, Niu;Zhang, Yufeng;Zhang, Youlin;Zhu, Kexue
关键词：coconut water; nutrition; volatile organic compounds; antioxidant activity
-
Biotransformation of HBCDs by the microbial communities enriched from mangrove sediments
作者：Yu, Fei;Zhang, Bing;Liu, Yongjin;Luo, Wenqi;Chen, Haonan;Gao, Jun'na;Peng, Tao;Wang, Hui;Huang, Tongwang;Hu, Zhong;Ye, Xueying;Li, Jin;Xie, Qingyi
关键词：Microbial community; HBCDs; Biotransformation; Dehalogenase
-
Widely targeted metabolomics combined with E-tongue and E-nose reveal dynamic changes of tender coconut water in responses to the infection of Ceratocystis paradoxa
作者：Shen, Xiaojun;Niu, Xiaoqing;Yang, Yaodong;Yang, Dejie;Li, Jing;Yu, Fengyu;Sun, Xiwei;Meng, Xiuli;Niu, Xiaoqing;Yang, Dejie;Yu, Fengyu;Meng, Xiuli
关键词：Cocos nucifera L.; Postharvest disease; Liquid endosperm; Flavor; Electronic sensing evaluation
-
Molecular mechanism of quality changes in solid endosperm of tender coconut during room temperature storage based on transcriptome and metabolome
作者：Shen, Xiaojun;Niu, Xiaoqing;Gong, Shufang;Sun, Xiwei;Xiao, Yong;Yang, Yaodong;Shen, Xiaojun;Xiong, Fei;Chen, Fusheng
关键词：Cocos nucifera Linn.; Solid endosperm; Postharvest storage; Transcriptome; Metabolome; Computed tomography (CT)
-
Harnessing nanobiotechnology for drought stress: transforming agriculture's future; what, why and how?
作者：Khan, Shahid Ullah;Wang, Hui;Qian, Mingchao;Lu, Kun;Khan, Shahid Ullah;Lu, Kun;Khan, Muhammad Sirab;Javed, Talha;Fahad, Shah;Fahad, Shah
关键词：
-
10-Hydroxydec-2-enoic acid enhances the erythrocyte membrane fluidity via interacting with phosphatidylcholine and phosphatidylethanolamine
作者：Sha, Fangfang;Yang, Peichang;Ren, Junhua;Li, Zirui;Zhang, Lu;Fan, Pei;Wang, Hui;Ren, Junhua
关键词：10-hydroxydec-2-enoic acid; erythrocyte; membrane; fluidity
