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Transcriptome analysis of castrated Bovine reveals the characters of protein accumulation

文献类型： 外文期刊

作者： Wang, Xi 1 ; Zhang, Yuanqing 2 ; Zhang, Xizhong 2 ; Jin, Guang 2 ; Wang, Dongcai 2 ; Li, Bo 2 ; Xu, Fang 2 ; Huang, Lisha 3 ;

作者机构： 1.Shanxi Agr Univ, Coll Anim Sci & Vet Med, Taigu 030801, Peoples R China

2.Shanxi Acad Agr Sci, Inst Anim Sci & Vet Med, Taiyuan 030032, Shanxi, Peoples R China

3.Biom Beijing Biotech Co Ltd, Beijing 100000, Peoples R China

关键词： Castration;PPAR pathway;Protein accumulation;RNA-seq

期刊名称：INDIAN JOURNAL OF ANIMAL RESEARCH （ 影响因子：0.44； 五年影响因子：0.543 ）

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收录情况： SCI

摘要： RNA-Seq, a new developing high-throughput sequencing technology in recent years, provides a new and more effective method for research in the genes' expression. The technology has been used to further improve our understanding on the function of the gene structure information and excavate the new transcripts and new genes. In this study, RNA-seq was employed to study the changes of the proteins after castration in cattle. The results showed the differential expression proteins between castrated cattle and noncastrated cattle were mainly lied in immunity, lipid and fatty acid metabolism and protein synthesis. Through GO and KEGG pathway enrichment analysis, the differential expression proteins were enriched in PPAR pathway which involved in meat quality traits and lipid metabolism and immunity. In addition, the genes were mainly involved in metabolic pathways, such as ECM-receptor, interaction MAPK, signaling pathway PPAR, protein phosphorylation. The function of the proteins involved in castration were not clear and needed further researches.

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