文献类型： 外文期刊

作者： Zhao, Zhanzhong ¹ ; Qin, Yuming ⁴ ; Lai, Zhi ¹ ; Peng, Liying ⁵ ; Cai, Xuehui ⁶ ; Wang, Liyong ⁴ ; Guo, Xin ¹ ; Yang, Han ¹ ;

作者机构： 1.China Agr Univ, Coll Vet Med, Minist Agr, Key Lab Zoonosis, Beijing 100193, Peoples R China

2.China Agr Univ, State Key Lab Agrobiotechnol, Beijing 100193, Peoples R China

3.Chinese Acad Agr Sci, Beijing Inst Anim Husb & Vet Med, Beijing 100193, Peoples R China

4.China Inst Vet Drug Control, Beijing 100081, Peoples R China

5.Shanghai Acad Agr Sci, Inst Anim Husb & Vet Med, Shanghai 201106, Peoples R China

6.Chinese Acad Agr Sci, Harbin Vet Res Ins

关键词： Microbial ecology;Swine farms;Porcine reproductive and respiratory syndrome;Attenuated vaccine;Vaccination strategies

期刊名称：VETERINARY MICROBIOLOGY （ 影响因子：3.293； 五年影响因子：3.599 ）

ISSN： 0378-1135

年卷期： 2012 年 155 卷 2-4 期

页码：

收录情况： SCI

摘要： The present study investigated the microbial ecology and vaccination strategies against porcine reproductive and respiratory syndrome (PRRS) in field condition. Four representative farms with a history of PRRS were included in this study. Over the almost 3-year period, the average detection rate was 68.9%, making PRRSV the first most frequently detected virus, followed by porcine circovirus type 2 (PCV2) (64.2%), pseudorabies virus (PRV) (11.03%) and classical swine fever virus (CSFV) (4.41%). Streptococcus suis (77.92%), Haemophilus parasuis (51.25%) and Escherichia coli (52.39%), Pasteurella multocida (26.77%) were isolated most frequently in association with PRRSV. Under the present microbial ecology, production performances of sows their offspring after mass vaccination with a PRRS attenuated vaccine were evaluated. In addition, large scale PRRS vaccines usage and efficacy were further performed. The results indicated that mass vaccination following our immunization program can improve health status and production performances of both sows (2 ml/i.m. booster after 4 weeks, and then immunized quarterly) and their offsprings (1 ml/i.m. on 14-18 days of age). (C) 2011 Elsevier B.V. All rights reserved.