Genetic Diversity of the Melanocortin 4 Receptor (MC4R) Gene and its Association with Slaughter Traits in the Landes Goose
文献类型： 外文期刊
作者： Huang, Yi 1 ; Wang, Yan 1 ; He, Daqian 2 ; Liu, Yiping 1 ;
作者机构： 1.Sichuan Agr Univ, Coll Anim Sci & Technol, Lab Anim Genet & Breeding, Yaan 625014, Sichuan, Peoples R China
2.Shanghai Acad Agr Sci, Inst Anim Husb & Vet Med, Shanghai 201106, Peoples R China
关键词： MC4R;Landes goose;SNP;Carcass trait;Haplotype
期刊名称：BIOCHEMICAL GENETICS （ 影响因子：1.89； 五年影响因子：1.959 ）
ISSN： 0006-2928
年卷期： 2010 年 48 卷 11-12 期
页码：
收录情况： SCI
摘要： Melanocortin 4 receptor (MC4R) plays a crucial part in regulating feeding behavior in humans and rodents. We detected two single nucleotide polymorphisms (SNPs; c.108G -> A and c.627C -> T) in the goose MC4R gene and genotyped 94 Landes geese for association analysis with several carcass traits. Significant associations (P < 0.05) were obtained for c.108G -> A with carcass weight, breast muscle percentage, and leg muscle percentage, and for c.627C -> T with body weight, carcass weight, semi-eviscerated weight, and eviscerated weight. We re-constructed haplotypes based on the two SNPs and analyzed diplotypes in association with carcass traits, obtaining significant associations with several of the traits. These results suggest that polymorphisms in the MC4R gene could have effects on carcass traits in Landes geese. More study is required to confirm these results.
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