Heterocyclic amines in cooked meat products, shortcomings during evaluation, factors influencing formation, risk assessment and mitigation strategies
文献类型： 外文期刊
作者： Khan, Iftikhar Ali 1 ; Khan, Asad 3 ; Zou, Ye 1 ; Zhu Zongshuai 4 ; Xu, Weimin 1 ; Wang, Daoying 1 ; Huang, Ming 4 ;
作者机构： 1.Jiangsu Acad Agr Sci, Inst Agr Prod Proc, Nanjing 210014, Peoples R China
2.Jiangsu Univ, Sch Food & Biol Engn, Zhenjiang 212013, Jiangsu, Peoples R China
3.Nanjing Agr Univ, Coll Prevent Vet Med, Key Lab Mucosal Immunol, Nanjing, Peoples R China
4.Nanjing Agr Univ, Coll Food Sci & Technol, Synerget Innovat Ctr Food Safety & Nutr, Nanjing Innovat Ctr Meat Prod Proc, Nanjing 210095, Jiangsu, Peoples R China
5.Shenzhen Univ, Inst Adv Study, Shenzhen Key Lab Marine Microbiome Engn, Shenzhen 518060, Peoples R China
关键词： Cooked meat; Heterocyclic amines; Cancer risk; Dietary intake; Mitigation strategies
期刊名称：MEAT SCIENCE （ 影响因子：7.077； 五年影响因子：6.632 ）
ISSN： 0309-1740
年卷期： 2022 年 184 卷
页码：
收录情况： SCI
摘要： At this point in time, the evidence of a link between well-done meat intake and the incidence of cancer is stronger than it was 20 years ago. Several cohort and case-control studies have confirmed this evidence, and have shown a higher odd ratio and increased exposure to heterocyclic amines (HCAs) among those who frequently consume red meat. However, in most epidemiological studies, dietary assessment, combined with analytical data, is used to estimate the intake of HCAs, which has many inconsistencies. In addition, there is a lack of findings indicating a substantial correlation between various factors, like types of raw meat, types of meat products, and cooking methods that directly or indirectly influence the occurrence of cancer. Although numerous mitigation strategies have been developed to reduce HCAs levels in meat, there is still a high prevalence of carcinogenesis caused by HCAs in humans. The aim of this review is to summarise conflicting reports, address shortcomings and identify emerging trends of cutting-edge research related to HCAs.
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