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Identification of Metabolized Polychlorinated Biphenyls in Fishery Products by Gas Chromatography-Tandem Mass Spectrometry

文献类型： 外文期刊

作者： Shi Yong-Fu 1 ; Cai You-Qiong 1 ; Yu Hui-Juan 1 ; Tian Liang-Liang 1 ; Huang Xuan-Yun 1 ; Huang Dong-Mei 1 ;

作者机构： 1.Chinese Acad Fishery Sci, Aquat Prod Qual Inspect & Test Ctr Shanghai, East China Sea Fisheries Res Inst, Minist Agr PR China, Shanghai 200090, Peoples R China

关键词： Gas chromatography-tandem mass spectrometry;Polychlorinated biphenyls;Metabolized pollutants;Hydroxylated polychlorinated biphenyls

期刊名称：CHINESE JOURNAL OF ANALYTICAL CHEMISTRY （ 影响因子：1.134； 五年影响因子：0.909 ）

ISSN： 0253-3820

年卷期： 2014 年 42 卷 11 期

页码：

收录情况： SCI

摘要： Gas chromatography. tandem mass spectrometry was adopted to identify the hydroxylated metabolites of polychlorinated biphenyls and analyze the target compounds in fishery products. After the silylation derivatizaiton at 60 degrees C for 40 min, the MS spectrum of derivatives was obtained by GC/MS/MS under fullscan mode, and the fragment ions with the highest relative abundance were identified as m/z 399, 399, 399, 399, 399, 448 and 469, respectively which were defined as the precursor ion for product ion scan. The MS/MS spectrum was obtained under multiple reaction mode (MRM) by GC/MS/MS. And the product ions corresponded with the precursor ions were m/z 364, 364, 364, 364, 364, 433 and 434, respectively. The target compounds can be identified accurately by GC/MS/MS. In the present study, we took seven hydroxylated polychlorinated biphenyls as target compounds including 3-OH-PCB101, 4-OH-PCB106, 4-OH-PCB112, 4'-OH-PCB101, 3-OH-PCB118, 3-OH-PCB138 and 3-OH-PCB180. According to the identification method stated as above, the MS and MS/MS spectra of seven compounds were obtained. The compounds can be qualified and quantified by the identification method. The limits of detection ranged from 0. 02 to 0. 14 mu g/L, and the limits of quantification ranged from 0. 09 to 0. 48 mu g/L. The method has been applied to identify the hydroxylated polychlorinated biphenyls in fishery products.

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