文献类型： 外文期刊

作者： Wang Song ¹ ; Li Ke ² ; Cui He ³ ; Wang Jing-Tang ³ ; Zhao Xin-Peng ¹ ; Miao Jun-Kui ¹ ; Liu Xiao-Fang ¹ ; Zhao Xian-Yong ¹ ;

作者机构： 1.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao 266071, Peoples R China

2.Michigan State Univ, Dept Fisheries & Wildlife, E Lansing, MI 48824 USA

3.Shandong Entry Exit Inspect & Quarantine Bur, Qingdao 266002, Peoples R China

关键词： Antartic krill oil;Arsenic;Speciation analysis;High performance liquid chromatography-inductively coupled plasma mass spectrometry

期刊名称：CHINESE JOURNAL OF ANALYTICAL CHEMISTRY （ 影响因子：1.134； 五年影响因子：0.909 ）

ISSN： 0253-3820

年卷期： 2016 年 44 卷 5 期

页码：

收录情况： SCI

摘要： Arsenic is a toxic metalloid that is abundant in many marine species, including Antartic krill. Krill oil is being developed for the health. food and dietary supplement because it possesses of omega. 3 fatty acids and phospholipid. derived fatty acids; however, it was limited due to its multiple arsenic species residues. Here, we presented a high performance liquid chromatography. inductively coupled plasma mass spectrometric (HPLC-ICP-MS) method for the simultaneous, sensitive, and rapid quantification of five arsenic metabolites including organic and inorganic forms, then the method was applied to the analysis of arsenic species in krill oil. The analytes were separated on a hydroxide-selective anion. exchange column with sodium carbonate (38 mmol/L) and sodium acetate (15 mmol/L) as mobile phase at a flow rate of 0.6 mL/min for 15 min. Arsenic analytes were monitored with a triple quadrupole ICP mass spectrometer. Validation revealed that the method had a linear range from 0.5 to 500 mu g/L with R > 0. 9993. The LOD was 0.1-0.2 mu g/L and LOQ was 1.5-2.6 mu g/L with RSD< 5%. The standard addition method displayed a recovery range from 88.9% to 106.3%. Application of the method to arsenic species analysis in krill oil indicated that krill oil was a safe food or diet supplement.