文献类型： 外文期刊
作者： Yang, Ying 1 ; Li, Yiming 1 ; Du, Xinglin 3 ; Liu, Zhiquan 5 ; Zhu, Chenxi 2 ; Mao, Weiping 2 ; Liu, Guoxing 1 ; Jiang, Qichen 1 ;
作者机构： 1.Freshwater Fisheries Res Inst Jiangsu Prov, Nanjing 210017, Peoples R China
2.Nanjing Normal Univ, Sch Life Sci, Inst Biochem & Biol Prod, Nanjing 210046, Peoples R China
3.East China Normal Univ, Sch Life Sci, Shanghai 200241, Peoples R China
4.Chinese Acad Fisheries Sci, Fishery Machinery & Instrument Res Inst, Shanghai 200092, Peoples R China
5.Hangzhou Normal Univ, Sch Life & Environm Sci, Hangzhou 311121, Zhejiang, Peoples R China
6.Hangzhou Normal Univ, Sch Engn, Hangzhou 310018, Zhejiang, Peoples R China
7.Freshwater Fisheries Res Inst Jiangsu Prov, Low Temp Germplasm Bank Important Econ Fish Jiangs, Nanjing 210017, Peoples R China
期刊名称：ACS OMEGA （ 影响因子：4.1； 五年影响因子：4.0 ）
ISSN： 2470-1343
年卷期： 2023 年 8 卷 20 期
页码：
收录情况： SCI
摘要： Quercetin is a flavonoid widely found in food and traditional herbs. In this study, we evaluated the anti-aging effects of quercetin on Simocephalus vetulus (S. vetulus) by assessing lifespan and growth parameters and analyzed the differentially expressed proteins and crucial pathways associated with quercetin activity using proteomics. The results demonstrated that, at a concentration of 1 mg/L, quercetin significantly prolonged the average and maximal lifespans of S. vetulus and increased the net reproduction rate slightly. The proteomics-based analysis revealed 156 differently expressed proteins, with 84 being significantly upregulated and 72 significantly downregulated. The protein functions were identified as being associated with glycometabolism, energy metabolism, and sphingolipid metabolism pathways, and the key enzyme activity and related gene expression, such that of AMPK, supported the importance of these pathways in the anti-aging activity of quercetin. In addition, quercetin was found to regulate the anti-aging-related proteins Lamin A and Klotho directly. Our results increased the understanding of quercetin's antiaging effects.
- 相关文献
作者其他论文 更多>>
-
Diversity of rhizosphere microbial communities in different rice varieties and their diverse adaptive responses to saline and alkaline stress
作者：Zhong, Yu;Wu, Tao;Fan, Wenbo;Su, Haoyu;Li, Ruoyu;Jiang, Wenzhu;Du, Xinglin;Ma, Ziming;Chi, Hai;Ma, Ziming
关键词：saline stress; alkaline stress; rice; rhizosphere microbiota; metagenomic analysis
-
Unraveling the stress response: How low temperature and nanoparticles impact the chinese mitten crab (Eriocheir sinensis)
作者：Zhou, Zihan;Wang, Lanmei;Zhou, Zihan;Tian, Jian;Jiang, Qichen;Zhou, Zihan;Tay, Yi Juin;Han, Mingming;Si, Qin
关键词：Eriocheir sinensis; Nanoplastics; PI3K-Akt-FoxO; Multi-omics
-
Comparative mechanisms of acute high-alkalinity stress on the normal and hybrid populations of pacific white shrimp (Litopenaeus vannamei)
作者：Ye, Yucong;Liu, Hang;Yuan, Haojuan;Du, Xinglin;Huang, Jiarong;Zhou, Yujie;Zhao, Yunlong;Li, Yiming
关键词：alkaline stress; gene expression; ion transport;
Litopenaeus vannamei ; nitrogen metabolism -
Spatial-temporal dynamics of marine microorganisms in Kuroshio-Oyashio Extension
作者：Zhao, Shanshan;Hu, Xin;Cheng, Yuan;Wang, Yuxuan;Li, Haoshuai;Zhang, Honghai;Li, Yiming;Bao, Mutai;Zhao, Shanshan;Hu, Xin;Cheng, Yuan;Wang, Yuxuan;Li, Haoshuai;Zhang, Honghai;Lu, Jinren;Li, Yiming;Bao, Mutai;Hu, Xin
关键词：Microorganisms; Biodiversity; Community composition; Spatial-temporal dynamic; Kuroshio-Oyashio Extension
-
Microplastic Ingestion by Fish with Different Feeding Habits from Different Habitats in a Typical Semi-Enclosed Haizhou Bay
作者：Sui, Yanming;Zhang, Yingying;Chen, Shihao;Shi, Yangyang;Zou, Jiaxin;Qin, Kunyun;Yu, Yebing;Lv, Linlan;Mohamed, Mohsen;Mohamed, Mohsen;Liu, Zhiquan;Sui, Yanming;Zheng, Liang
关键词：microplastics; semi-enclosed bay; feeding habits; feeding modes
-
Ion transport and metabolic regulation induced by nanoplastic toxicity in gill of Litopenaeus vannamei using proteomics
作者：Li, Yiming;Yao, Zongli;Li, Yan;Sun, Zhen;Lai, Qifang;Ye, Yucong;Zhu, Xiaoyi;Rihan, Na;Zhao, Yunlong
关键词：
-
Transcriptome Analysis Reveals the Key Genes and Pathways for Growth, Ion Transport, and Oxidative Stress in Post-Larval Black Tiger Shrimp (Penaeus monodon) Under Acute Low Salt Stress
作者：Li, Yiming;Gao, Pengcheng;Li, Yan;Sun, Zhen;Li, Longyi;Zhou, Kai;Wei, Yuxing;Yao, Zongli;Lai, Qifang;Ye, Yucong
关键词：Ion transport;
Penaeus monodon ; Low salt; Transcriptome analysis; Gene expression
