Identification of 2,2',4,5,5' -Pentachlorobiphenyl (PCB101) metabolites and their transmission characteristics in silver crucian carp (Carassius auratus gibelio)
文献类型： 外文期刊
作者： Wang, Shuai 1 ; Wang, Meng-Yuan 1 ; Shi, Yong-Fu 1 ; Han, Feng 1 ; Ye, Hong-Li 1 ; Cai, You-Qiong 1 ; Wu, Di 1 ; Tian, Liang-Liang 1 ; Zhang, Xuan 1 ; Tang, Yun-Yu 1 ;
作者机构： 1.Chinese Acad Fishery Sci, East China Sea Fisheries Res Inst, Fishery Prod Qual Inspection & Test Ctr Shanghai, Key Lab East China Sea Fishery Resources Exploitat, 300 Jungong Rd, Shanghai 200090, Peoples R China
2.Shanghai Ocean Univ, Coll Food Sci & Technol, Shanghai 201306, Peoples R China
3.Linquan Cty Agr Prod Qual & Safety Inspection Stn, Linquan, Anhui, Peoples R China
关键词： PCB101; Metabolite; Identification; Transfer characteristics; GC-MS/MS
期刊名称：ENVIRONMENTAL POLLUTION （ 影响因子：9.988； 五年影响因子：10.366 ）
ISSN： 0269-7491
年卷期： 2022 年 307 卷
页码：
收录情况： SCI
摘要： Polychlorinated biphenyls (PCBs) have been attracting global concern due to their persistence and toxicity. However, the study on the metabolites of PCBs in freshwater fish is limited. In this study, the metabolites of 2,2',4,5,5'-Pentachlorobiphenyl (PCB101) in silver crucian carp (Carassius auratus gibelio) were identified for the first time. After intraperitoneal injection of PCB101 (2 mg/kg), the results showed that it could be metabolized to at least three types of metabolites, including hydroxylated (OH-), methoxylated (MeO-) and methyl sulfonated (MeSO2-) PCB101. The OH-metabolites identified in most tissues were 3-OH-PCB101and 4-OH-PCB101, such as liver, gallbladder, blood and muscle. MeSO2- metabolites identified in gallbladder, blood and brain were 3-MeSO2-PCB101 and 4-MeSO2-PCB101. Meanwhile, the MeO-metabolite identified in liver, gallbladder, blood and spleen of silver crucian carp was 4-MeO-PCB101. The investigation of the types and structures of PCB101 and its metabolites, as well as the tissue distribution and accumulation characteristics in silver crucian carp are beneficial to understand the transformation and metabolic mechanisms of PCBs in aquatic organisms. It is of great significance to identify potential pollution hazards of precursor compounds and their metabolites on aquatic products and ensure the quality and safety of aquatic products.
- 相关文献
作者其他论文 更多>>
-
Effects of steaming practices on the cadmium distribution in edible tissues of the swimming crabs (Portunus trituberculatus) and its health risk assessment
作者：Wu, Di;Mo, Xiao;Zhang, Xiaoying;Shi, Yongfu;Huang, Dongmei;Fang, Changling;Tang, Yunyu;Han, Feng;Tian, Liangliang;Li, Siman;Wu, Di;Mo, Xiao;Zhang, Xiaoying
关键词：Steaming; Cadmium; Portunus trituberculatus; Redistribution; Health risk; Brown meat
-
Cottonseed protein concentrate as an effective substitute to fish meal in pike perch (Sander luciperca) feed: evidence from growth performance and intestinal responses of immune function and microflora
作者：Fan, Ze;Zhao, Jie;Lu, Cuiyun;Wu, Di;Sun, Zhipeng;Li, Jinnan;Wang, Liansheng;Zheng, Xianhu;Zhao, Jie;Huang, Jiaming
关键词：pikeperch (
Sander luciperca ); cottonseed protein concentrate (CPC); 60% substitution ratio for fish meal; decreasedigf1 expression; intestinal microflora -
Assessment on Chlorella (Chlorella sorokiniana) meal as a substitution for fishmeal in Songpu mirror carp (Cyprinus carpio Songpu) feed: Effect on growth, intestinal health and microflora composition
作者：Fan, Ze;Gao, Yiqi;Li, Chenhui;Wu, Di;Li, Jinnan;Wang, Liansheng;Gao, Yiqi;Xiong, Siwei;Li, Chenhui
关键词：Chlorella; Songpu mirror carp; Growth performance; Serum biochemistry; Intestinal health
-
Developing a mutant strain of Pseudomonas composti ODT-54 for enhanced production of Psl extracellular polysaccharide
作者：Wu, Jieer;Yu, Yongxin;Wang, Yongjie;Wang, Yongjie;Han, Feng;Han, Feng
关键词：
Pseudomonas composti ; Psl EPS; Arabinose promoter; Overexpression -
Simultaneous Determination of Four Off-flavors in Freshwater Fish by Gas Chromatography-Mass Spectrometry Combined with Silica Solid Phase Extraction
作者：Tian, Liang-Liang;Shi, Yong-Fu;Ye, Hong-Li;Huang, Dong-Mei;Wang, Yuan;Huang, Xuan-Yun
关键词：Odors; n-Hexane; Silica solid phase extraction; Gas chromatography-mass spectrometry; Fresh water fish
-
Effects of acute cadmium exposure on biochemistry, liver oxidative stress and transcriptomics in Songpu mirror carp (Cyprinus carpio Songpu)
作者：Fan, Ze;Wang, Yan;Li, Chenhui;Wu, Di;Wang, Liansheng;Li, Jinnan;Li, Jiaxin;Wang, Yan;Li, Jiaxin;Li, Chenhui;Miao, Linghong;Xu, Hong
关键词：Glucose abnormalities; Immune barrier; Lipid metabolism disorder; Oxidative damage; Songpu mirror carp
-
Integrated Metagenomic and LC-MS/MS Analysis Reveals the Biogenic Amine-Producing Strains of Two Typical Chinese Traditional Fish Products: Fermented Mandarin Fish (Siniperca chuatsi) and Semi-Dried Yellow Croaker (Larimichthys crocea)
作者：Zhang, Xuan;Peng, Di;Jiang, Mei;Wang, Cuihua;Zhang, Haiyan;Kang, Wei;Li, Lei;Chi, Hai
关键词：metagenomes; microbial community; biogenic amine-producing bacteria; biogenic amines; fish product
