您好，欢迎访问河南省农业科学院 机构知识库！
河南省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Are the two polymorphic sites of anti-Marek's disease in White Leghorn chickens also suitable for Partridge Shank chickens?

文献类型： 外文期刊

作者： Li, Wenqing 1 ; Li, Wanli 2 ; Wang, Bei 1 ; Zhang, Lin 1 ; Li, Shengli 3 ; Li, Henwan 1 ; Wu, Pinhui 1 ; Yang, Guoqing 1 ; Zhang, Guozhi 1 ;

作者机构： 1.Henan Agr Univ, Coll Life Sci, Anim Genet Engn Lab, Zhengzhou 450002, Peoples R China

2.Shennong Lab, Zhengzhou 450002, Peoples R China

3.Henan Acad Agr Sci, Inst Anim Husb & Vet Sci, Zhengzhou 450002, Peoples R China

期刊名称：BIOCELL （ 影响因子：1.2； 五年影响因子：1.1 ）

ISSN： 0327-9545

年卷期： 2023 年 47 卷 5 期

页码：

收录情况： SCI

摘要： Background: The selection of Marek's disease (MD)-resistant breeds in Partridge Shank chicken, a popular local chicken breed in Henan Province of China, has practical value. We hypothesized that the two polymorphic sites (rs14527240 located in SMOC1 and GGaluGA156129 located in PTPN3) related to MD resistance in White Leghorn chickens are also applicable to Partridge Shank chickens. Methods: In this experiment, we screened 10 live hens and 2 live roosters with the double GG genotype by genotyping the two sites from 6500 Partridge Shank chickens. Nineteen one-day-old chicks with the double GG genotype were obtained by artificial insemination. Seventy-two one-day-old chickens (19 from the population expansion test and 53 randomly selected from chicken farms) were injected with 2000 plaque-forming units of the Md5 virus strain. After 100 days of infection, all chickens were examined by pathological anatomical examination, histological sectioning, genotyping, and a quantitative polymerase chain reaction of SMOC1 and PTPN3.Results: There was only one site (rs14527240 located in SMOC1) associated with MD in Partridge Shank chickens (p < 0.05), but the GG genotype of SMOC1 in Partridge Shank chickens indicated susceptibility to MD. SMOC1 expression in MD-susceptible chickens was also significantly higher than that in MDresistant chickens (p < 0.05).Conclusion: Therefore, the MD resistance sites selected from White Leghorn chickens were not completely suitable for Partridge Shank chickens, but they can be used as a reference. This study indicated that SMOC1 plays an important role in screening for MD resistance in poultry.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：河南省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台