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Behavioral Fever in Lined Seahorse (Hippocampus erectu) Enhances the Immune Response to Vibrio harveyi Infection

文献类型： 外文期刊

作者： Li, Siping 1 ; Liu, Xin 1 ; Lin, Tingting 1 ; Zhang, Dong 2 ;

作者机构： 1.Chinese Acad Fishery Sci, East China Sea Fisheries Res Inst, Key Lab Inland Saline Alkaline Aquaculture, Minist Agr & Rural Affairs, Shanghai 200090, Peoples R China

2.Shangdong Qianyuan Biotech Co Ltd, Bingzhou 256600, Peoples R China

关键词： lined seahorse; behavioral fever; thermoregulation; immune response; temperature

期刊名称：ANIMALS （ 影响因子：2.7； 五年影响因子：3.2 ）

ISSN： 2076-2615

年卷期： 2025 年 15 卷 11 期

页码：

收录情况： SCI

摘要： In this study, polyethersulfone (PES)/sulfonated polyethersulfone (SPES) composite nanofiltration membranes doped with different contents of monolayer titanium carbide nanosheets (Ti3C2TX) were prepared by the nonsolvent induced phase inversion (NIPS) method. The effects of Ti3C2TX on membrane structure, separation performance and antibacterial activity were investigated systematically. The results demonstrated that the viscosity of the casting solution increased significantly with the increasing content of Ti3C2TX. In addition, the pore size of the membrane surface first decreased and then increased; porosity and hydrophilicity were optimized synchronously; and the density of negative charges on the surface increased. The M2 membrane showed a rejection rate of more than 90% for Metanil yellow (MY) and methylene blue (MEB). The order of salt ion rejection rates was magnesium sulfate (MgSO4) > sodium sulfate (Na2SO4) > sodium chloride (NaCl), and water flux reached the peak (18.5 L/m(2)hbar). The antibacterial activity of the M2 membrane was significantly enhanced, and its antibacterial rate against Bacillus subtilis increased from 15% (M0) to 58%. This phenomenon was attributed to the synergistic mechanism of the Ti3C2TX physical capture effect, reactive oxygen species (ROS) generation and sharp edge damage to bacterial cell membranes. This study provides theoretical support and a technical path for the development of MXene composite membranes with high separation efficiency and excellent antibacterial properties.

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