您好，欢迎访问浙江省农业科学院 机构知识库！
浙江省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Current opinions on mitophagy in fungi

文献类型： 外文期刊

作者： Shen, Zi-Fang 1 ; Li, Lin 1 ; Zhu, Xue-Ming 1 ; Liu, Xiao-Hong 2 ; Klionsky, Daniel J. 3 ; Lin, Fu-Cheng 1 ;

作者机构： 1.Zhejiang Acad Agr Sci, Inst Plant Protect & Microbiol, State Key Lab Managing Biot & Chem Treats Qual &, Hangzhou 310021, Zhejiang, Peoples R China

2.Zhejiang Univ, Inst Biotechnol, State Key Lab Managing Biot & Chem Treats Qual &, Hangzhou, Zhejiang, Peoples R China

3.Univ Michigan, Life Sci Inst, Ann Arbor, MI 48109 USA

4.Univ Michigan, Dept Mol Cellular & Dev Biol, Ann Arbor, MI 48109 USA

关键词： Fission; fungi; mitochondria; mitophagy; pathogenesis; quantity and quality control

期刊名称：AUTOPHAGY （ 影响因子：13.391； 五年影响因子：16.142 ）

ISSN： 1554-8627

年卷期：

页码：

收录情况： SCI

摘要： Mitophagy, as one of the most important cellular processes to ensure quality control of mitochondria, aims at transporting damaged, aging, dysfunctional or excess mitochondria to vacuoles (plants and fungi) or lysosomes (mammals) for degradation and recycling. The normal functioning of mitophagy is critical for cellular homeostasis from yeasts to humans. Although the role of mitophagy has been well studied in mammalian cells and in certain model organisms, especially the budding yeast Saccharomyces cerevisiae, our understanding of its significance in other fungi, particularly in pathogenic filamentous fungi, is still at the preliminary stage. Recent studies have shown that mitophagy plays a vital role in spore production, vegetative growth and virulence of pathogenic fungi, which are very different from its roles in mammal and yeast. In this review, we summarize the functions of mitophagy for mitochondrial quality and quantity control, fungal growth and pathogenesis that have been reported in the field of molecular biology over the past two decades. These findings may help researchers and readers to better understand the multiple functions of mitophagy and provide new perspectives for the study of mitophagy in fungal pathogenesis.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：浙江省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台