文献类型： 外文期刊
作者： Song, Chunjie 1 ; Gan, Shangquan 2 ; He, Jian 1 ; Shen, Xiaoyun 1 ;
作者机构： 1.Southwest Univ Sci & Technol, Sch Life Sci & Engn, Mianyang 621010, Sichuan, Peoples R China
2.Xinjiang Acad Agr & Reclamat Sci, State Key Lab Sheep Genet Improvement & Hlth Prod, Shihezi 832000, Xinjiang, Peoples R China
3.World Bank Poverty Alleviat Project Off Guizhou S, Guiyang 550004, Peoples R China
关键词： Zinc deprivation; Nano-zinc; The Qianbei-pockmarked goats; Blood parameters; Immunity
期刊名称：BIOLOGICAL TRACE ELEMENT RESEARCH （ 影响因子：3.738； 五年影响因子：3.44 ）
ISSN： 0163-4984
年卷期：
页码：
收录情况： SCI
摘要： Qianbei-pockmarked goats are vital to the production system of western China. This study aimed to determine the influence of nano-zinc on immune function in zinc-deprived goats. We analyzed the mineral concentrations in soil, forage, and animal tissue. Blood parameters and immune indexes were also determined. Results showed that the zinc concentrations in soil and forage from affected area were significantly lower than those in control area (P < 0.01). Zinc contents in tissues (blood and hair) from affected Qianbei-pockmarked goats were also significantly lower than those in healthy animals (P < 0.01). Levels of hemoglobin, erythrocyte count, and packed cell volume from affected animals were markedly lower than those in healthy animals (P < 0.01). Levels of lactate dehydrogenase, alkaline phosphatase, superoxide dismutase, glutathione peroxide, catalase, and total antioxidant capacity in serum in affected animals were significantly lower, and aspartate aminotransferase, alanine transaminase, malondialdehyde in serum were significantly higher than those in healthy goats (P < 0.01). The contents of immunoglobulin A, immunoglobulin M, immunoglobulin G, interleukin-2, interleukin 6, and interleukin-1 beta from affected animals were significantly lower than those in healthy animals (P < 0.01). The affected Qianbei-pockmarked goats were treated orally with nano-zinc, the concentration of zinc in blood significantly increased, and serum immune indexes greatly returned to that within the healthy range. It was concluded that nano-zinc could not only markedly increase the zinc content in blood of zinc-deprived goats but also much improve the immune function.
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