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New paraconic acids from the endophytic fungus Xylariaceae sp. J4

文献类型: 外文期刊

作者: Yuan, Chao 1 ; Shu, Xue-Chun 2 ; Fan, Lin 3 ; Zhang, Ying-Bo 1 ; Guan, Ling-Liang 1 ; Yu, Fu-Lai 1 ; Chen, Xiao-Lu 1 ; Li 1 ;

作者机构: 1.Chinese Acad Trop Agr Sci, Hainan Prov Engn Res Ctr Trop Med Plants, Trop Crops Genet Resources Inst, Danzhou, Peoples R China

2.Hainan Univ, Coll Forestry, Haikou, Hainan, Peoples R China

3.Weihai Vocat Coll, Dept Biol & Chem Engn, Weihai, Peoples R China

4.Qingdao Univ, Sch Pharm, Dept Nat Med Chem & Pharmacognosy, Qingdao 266021, Peoples R China

关键词: Endophytes; Xylariaceae sp; secondary metabolites; paraconic acids; antibacterial activities

期刊名称:NATURAL PRODUCT RESEARCH ( 影响因子:2.861; 五年影响因子:2.572 )

ISSN: 1478-6419

年卷期:

页码:

收录情况: SCI

摘要: Three new paraconic acids, xylariacinics A-C (1-3), were isolated from the endophyte Xylariaceae sp. J4 harbored in the medicinal plant Blumea balsamifera. Their structures were elucidated on the basis of extensive spectroscopic data including HRMS, and NMR. The antibacterial efficacies of compounds 1-3 were evaluated against a panel of bacteria such as Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa. Their antifungal activities were also tested against Colletotrichum gloeosporioides. Unfortunately, all of them were inactive.

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