文献类型： 外文期刊

作者： Yang Yibin ¹ ; Chen Yuhua ⁴ ; Liu Yongtao ¹ ; Song Yi ² ; Ai Xiaohui ¹ ;

作者机构： 1.Chinese Acad Fishery Sci, Yangtze River Fisheries Res Inst, Wuhan 430223, Peoples R China

2.Minist Agr, Key Lab Qual & Safety Control Aquat Prod, Beijing, Peoples R China

3.Shanghai Ocean Univ, Natl Demonstrat Ctr Expt Fisheries Sci Educ, Shanghai, Peoples R China

4.Wuhan Univ, Dept Gastroenterol, Zhongnan Hosp, Wuhan 430227, Peoples R China

5.Hubei Clin Ctr, Wuhan, Peoples R China

6.Key Lab Intestinal & Colorectal Dis, Wuhan, Peoples R China

关键词： Hirudo nipponia; humans; Klebsiella pneumoniae; pathogenic bacteria

期刊名称：TRANSBOUNDARY AND EMERGING DISEASES （ 影响因子：5.005； 五年影响因子：4.622 ）

ISSN： 1865-1674

年卷期：

页码：

收录情况： SCI

摘要： Hirudo nipponia,or the leech, is not only an important economic pillar for farmers, but is also a precious raw material for medicinal materials. However, in recent years,H. nipponiahas suffered from disease with symptoms including systemic oedema and hyperaemia. It has not yet been demonstrated which pathogen causes this disease and whether this could be transmitted to humans. In this study,Klebsiella pneumoniaewas isolated and identified and the pathogenicity of the isolated strain was confirmed. Furthermore, by comparing the sequence of the pathogen isolated from leeches to the same pathogen infecting humans, we identified that the isolated strain is a threat to human health. This work emphasizes the importance of the first discovery of pathogenic bacteria from leeches similar to human pathogens, as well as the need for identifying zoonosis for both humans and aquatic animals.