文献类型： 外文期刊
作者： Liang, Ji 2 ; Ji, Feng 1 ; Abdullah, Anisah Lee Binti 2 ; Qin, Wei 3 ; Zhu, Tian 2 ; Tay, Yi Juin 2 ; Li, Yiming 4 ; Han, Mingming 2 ;
作者机构： 1.Southeast Univ, Zhongda Hosp, Med Sch, Dept Clin Sci & Res, Nanjing 210009, Peoples R China
2.Univ Sains Malaysia, Minden 11800, Penang, Malaysia
3.Nanjing Med Univ, Nanjing Hosp 1, Dept Cardiothorac Surg, Nanjing 211166, Peoples R China
4.Chinese Acad Fisheries Sci, Fishery Machinery & Instrument Res Inst, Shanghai 200092, Peoples R China
关键词： Microplastics; Nano-plastics; Cardiovascular system; Blood vessels; Heart
期刊名称：SCIENCE OF THE TOTAL ENVIRONMENT （ 影响因子：8.2； 五年影响因子：8.6 ）
ISSN： 0048-9697
年卷期： 2024 年 942 卷
页码：
收录情况： SCI
摘要： The widespread presence of microplastics and nanoplastics (MPs/NPs) in the environment has become a critical public health issue due to their potential to infiltrate and affect various biological systems. Our review is crucial as it consolidates current data and provides a comprehensive analysis of the cardiovascular impacts of MPs/NPs across species, highlighting significant implications for human health. By synthesizing findings from studies on aquatic and terrestrial organisms, including humans, this review offers insights into the ubiquity of MPs/NPs and their pathophysiological roles in cardiovascular systems. We demonstrated that exposure to MPs/NPs is linked to various cardiovascular ailments such as thrombogenesis, vascular damage, and cardiac impairments in model organisms, which likely extrapolate to humans. Our review critically evaluated methods for detecting MPs/NPs in biological tissues, assessing their toxicity, and understanding their behaviour within the vasculature. These findings emphasise the urgent need for targeted public health strategies and enhanced regulatory measures to mitigate the impacts of MP/NP pollution. Furthermore, the review underlined the necessity of advancing research methodologies to explore long-term effects and potential intergenerational consequences of MP/NP exposure. By mapping out the intricate links between environmental exposure and cardiovascular risks, our work served as a pivotal reference for future research and policymaking aimed at curbing the burgeoning threat plastic pollution.
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