您好，欢迎访问广东省农业科学院 机构知识库！
广东省农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Integrated analysis of intestinal microbiota and transcriptome reveals that a coordinated interaction of the endocrine, immune system and gut microbiota response to heat stress in Litopenaeus vannamei

文献类型： 外文期刊

作者： Liao, Guowei 1 ; Wang, Wanqi 1 ; Yu, Jiaoping 1 ; Li, Jingping 1 ; Yan, Yumeng 1 ; Liu, Haolin 1 ; Chen, Bing 2 ; Fan, Lanfen 1 ;

作者机构： 1.South China Agr Univ, Coll Marine Sci, Guangzhou 510642, Peoples R China

2.Guangdong Acad Agr Sci, Key Lab Anim Nutr & Feed Sci South China, Guangdong Key Lab Anim Breeding & Nutr, Minist Agr Rural Affairs,Inst Anim Sci, Guangzhou 510640, Peoples R China

3.South China Agr Univ, Coll Marine Sci, 483 Wushan St, Guangzhou 510642, Guangdong, Peoples R China

关键词： Litopenaeus vannamei; Heat stress; Oxidative stress; Intestinal microbiota; Transcriptome

期刊名称：DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY （ 影响因子：2.9； 五年影响因子：3.1 ）

ISSN： 0145-305X

年卷期： 2024 年 156 卷

页码：

收录情况： SCI

摘要： Due to the ongoing global warming, the risk of heatwaves in the oceans is continuously increasing while our understanding of the physiological response of Litopenaeus vannamei under extreme temperature conditions remains limited. Therefore, this study aimed to evaluate the physiological responses of L. vannamei under heat stress. Our results indicated that as temperature rose, the structure of intestinal and hepatopancreatic tissues was damaged sequentially. Activity of immune -related enzymes (acid phosphatase/alkaline phosphatase) initially increased before decreased, while antioxidant enzymes (superoxide dismutase and glutathione-S transferase) activity and malondialdehyde content increased with rising temperature. In addition, the total antioxidant capacity decreased with rising temperature. With the rising temperature, there was a significant increase in the expression of caspase-3, heat shock protein 70, lipopolysaccharide-induced tumor necrosis factor- alpha, transcriptional enhanced associate domain and yorkie in intestinal and hepatopancreatic tissues. Following heat stress, the number of potentially beneficial bacteria ( Rhodobacteraceae and Gemmonbacter ) increased which maintain balance and promote vitamin synthesis. Intestinal transcriptome analysis revealed 852 differentially expressed genes in the heat stress group compared with the control group. KEGG functional annotation results showed that the endocrine system was the most abundant in Organismal systems followed by the immune system. These results indicated that heat stress leads to tissue damage in shrimp, however the shrimp may respond to stress through a coordinated interaction strategy of the endocrine system, immune system and gut microbiota. This study revealed the response mechanism of L. vannamei to acute heat stress and potentially provided a theoretical foundation for future research on shrimp environmental adaptations.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：广东省农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台