文献类型： 外文期刊
作者： Han, Mingming 2 ; Liu, Huaqiang 4 ; Zhu, Tian 2 ; Tang, Shengkai 1 ; Li, Yiming 5 ; Zhu, Chenxi 3 ; Zhou, Zihan 1 ; Jiang, Qichen 1 ;
作者机构： 1.Freshwater Fisheries Res Inst Jiangsu Prov, 79 Chating East Rd, Nanjing 210017, Peoples R China
2.Univ Sains Malaysia, Ctr Marine & Coastal Studies, Minden 11800, Penang, Malaysia
3.Univ Sains Malaysia, Sch Humanities, Geog, Minden 11800, Penang, Malaysia
4.Univ Sains Malaysia, Inst Res Mol Med, Minden 11800, Penang, Malaysia
5.Chinese Acad Fisheries Sci, Fishery Machinery & Instrument Res Inst, Shanghai 200092, Peoples R China
关键词： Microplastics; Toxic effects; Immunomodulation; Detection methods; Treatment
期刊名称：TRAC-TRENDS IN ANALYTICAL CHEMISTRY （ 影响因子：13.1； 五年影响因子：13.1 ）
ISSN： 0165-9936
年卷期： 2024 年 172 卷
页码：
收录情况： SCI
摘要： Microplastics and nanoplastics are emerging pollutants with minute particle size and significant specific surface area. These particles can harm organisms at tissue, cellular, and molecular levels, affecting microorganisms, plants, fish, mammals, and other species. This study investigates the mechanisms underlying microplastics' assimilation and associated contaminants by terrestrial organisms and humans, with a focus on detrimental impacts. Exposure to microplastics triggered oxidative stress, inflammatory damage, disrupted energy and lipid metabolism, and impaired intestinal function, impeding growth and development. Chronic inflammation and increased risk of inflammatory disorders in the digestive, respiratory, and reproductive systems may result from the immune system's failure to eliminate synthetic particles promptly. The study explored immune modulation and potential therapeutic interventions against microplastic invasion, along with detection and treatment methods in organisms to inform the future management of microplastic-induced diseases.
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