您好，欢迎访问中国水产科学研究院 机构知识库！
中国水产科学研究院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Hepatoprotective and antioxidant effects of Glycyrrhiza glabra extract against carbon tetrachloride (CCl4)-induced hepatocyte damage in common carp (Cyprinus carpio)

文献类型： 外文期刊

作者： Yin, Guojun 1 ; Cao, Liping 2 ; Xu, Pao 2 ; Jeney, Galina 3 ; Nakao, Miki 4 ; Lu, Chengping 1 ;

作者机构： 1.Nanjing Agr Univ, Wuxi Fisheries Coll, Wuxi 214081, Peoples R China

2.Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Minist Agr, Key Open Lab Genet Breeding Aquat Anim & Aquacult, Wuxi 214081, Peoples R China

3.Res Inst Fisheries Aquaculture & Irrigat, H-4440 Szarvas, Hungary

4.Kyushu Univ, Grad Sch Bioresource & Bioenvironm, Marine Biochem Lab, Fukuoka 8128581, Japan

关键词： Glycyrrhiza glabra;Carbon tetrachloride;Hepatocytes;Hepatoprotection;Antioxidant;Cyprinus carpio

期刊名称：FISH PHYSIOLOGY AND BIOCHEMISTRY （ 影响因子：2.794； 五年影响因子：2.876 ）

ISSN： 0920-1742

年卷期： 2011 年 37 卷 1 期

页码：

收录情况： SCI

摘要： The present study is aiming at evaluating the hepatoprotective and antioxidant effects of Glycyrrhiza glabra extract (2.5, 5 and 10 mu g/ml) on the carbon tetrachloride (CCl4)-induced carp hepatocyte damage in vitro. Glycyrrhiza glabra extract was added to the carp primary hepatocytes before (pre-treatment), after (post-treatment) and both before and after (pre- and post-treatment) the incubation of the hepatocytes with CCl4. CCl4 at 8 mM in the culture medium produced significantly elevated levels of lactate dehydrogenase (LDH), glutamate oxalate transaminase (GOT), glutamate pyruvate transaminase (GPT) and malondialdehyde (MDA) and significantly reduced levels of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px). Pre-treatment (5 mu g/ml) and pre- and post-treatment (5 and 10 mu g/ml) of the hepatocytes with Glycyrrhiza glabra extract significantly reduced the elevated levels of LDH, GOT, GPT and MDA and increased the reduced levels of SOD and GSH-Px by CCl4; post-treatment of the hepatocytes with Glycyrrhiza glabra extract at 5 mu g/ml reduced the GPT and GOT levels and increased the GSH-Px level, but had no effect on the other parameters at all the studied concentrations. The results support the use of Glycyrrhiza glabra extract as a hepatoprotective and antioxidant agent in fish.

  • 相关文献

[1]Hepatoprotective and antioxidant effects of Hibiscus sabdariffa extract against carbon tetrachloride-induced hepatocyte damage in Cyprinus carpio. Yin, Guojun,Cao, Liping,Xu, Pao,Jeney, Galina,Nakao, Miki. 2011

[2]The protective effect of silymarin on the carbon tetrachloride (CCl4)-induced liver injury in common carp (Cyprinus carpio). Jia, Rui,Cao, Liping,Du, Jinliang,Xu, Pao,Yin, Guojun,Jeney, Galina. 2013

[3]Protective effects of Lycium barbarum polysaccharides against carbon tetrachloride-induced hepatotoxicity in precision-cut liver slices in vitro and in vivo in common carp (Cyprinus carpio L.). Liu, Yingjuan,Jia, Rui,Wang, Jiahao,Yin, Guojun,Cao, Liping,Du, Jinliang,Xu, Pao,Yin, Guojun,Cao, Liping,Du, Jinliang,Xu, Pao,Yin, Guojun. 2015

[4]Protective action of the phyllanthin against carbon tetrachloride-induced hepatocyte damage in Cyprinus carpio. Jia, Rui,Liu, Ying-Juan,Xu, Pao,Yin, Guo-Jun,Jia, Rui,Du, Jin-Liang,Cao, Li-Ping,Xu, Pao,Yin, Guo-Jun,Du, Jin-Liang,Cao, Li-Ping,Xu, Pao,Yin, Guo-Jun.

[5]Effects of carbon tetrachloride on oxidative stress, inflammatory response and hepatocyte apoptosis in common carp (Cyprinus carpio). Jia, Rui,Wang, Jia-Hao,Liu, Ying-Juan,Xu, Pao,Yin, Guo-Jun,Jia, Rui,Cao, Li-Ping,Du, Jin-Liang,Xu, Pao,Yin, Guo-Jun,Cao, Li-Ping,Du, Jin-Liang,Yin, Guo-Jun,Jeney, Galina.

[6]Hepatoprotective and antioxidant effects of phyllanthin against carbon tetrachloride-induced liver injury in Cyprinus carpio. Jia, Rui,Du, Jin-Liang,Cao, Li-Ping,Xu, Pao,Yin, Guo-Jun,Jia, Rui,Liu, Ying-Juan,Xu, Pao,Yin, Guo-Jun,Du, Jin-Liang,Cao, Li-Ping,Yin, Guo-Jun.

[7]Differentially Gene Expression in the Brain of Common Carp ( Cyprinus carpio ) Response to Cold Acclimation. Liqun Liang,Shaowu Li,Yumei Chang,Yong Li,Xiaowen Sun,Qingquan Lei. 2008

[8]Protective effect of Ganoderma lucidum polysaccharide against carbon tetrachloride-induced hepatic damage in precision-cut carp liver slices. Liu, Yingjuan,Zhang, Chunyun,Yin, Guojun,Du, Jinliang,Jia, Rui,Cao, Liping,Xu, Pao,Yin, Guojun,Du, Jinliang,Jia, Rui,Cao, Liping,Xu, Pao,Yin, Guojun,Jeney, Galina,Teraoka, Hiroki.

[9]Hepatoprotective and antioxidant effects of dietary Angelica sinensis extract against carbon tetrachloride-induced hepatic injury in Jian Carp (Cyprinus carpio var. Jian). Cao, Liping,Du, Jinliang,Ding, Weidong,Xu, Pao,Yin, Guojun,Cao, Liping,Du, Jinliang,Liu, Yingjuan,Xu, Pao,Yin, Guojun,Jia, Rui,Liu, Yingjuan,Teraoka, Hiroki.

[10]QTL variations for growth-related traits in eight distinct families of common carp (Cyprinus carpio). Lv, Weihua,Yan, Yunqin,Lv, Weihua,Zheng, Xianhu,Kuang, Youyi,Cao, Dingchen,Sun, Xiaowen. 2016

[11]Effects of three strains of intestinal autochthonous bacteria and their extracellular products on the immune response and disease resistance of common carp, Cyprinus carpio. Chi, Cheng,Jiang, Bing,Yu, Xiao-Bo,Liu, Tian-Qiang,Wang, Gao-Xue,Xia, Lei. 2014

[12]Development and evaluation of the first high-throughput SNP array for common carp (Cyprinus carpio). Xu, Jian,Zhao, Zixia,Li, Jiongtang,Jiang, Yanliang,Zhang, Yan,Li, Qiang,Zhu, Yuanyuan,Liu, Yuanyuan,Xu, Peng,Sun, Xiaowen,Zhang, Xiaofeng,Zheng, Xianhu,Kuang, Youyi,Sun, Xiaowen,Feng, Jianxin,Li, Chuangju,Yu, Juhua,Xu, Peng. 2014

[13]Effects of glutamine and its precursors on the growth performance and relevant protein synthesis pathway of mirror carp Cyprinus carpio. Zhao, Zhigang,Xu, Qiyou,Song, Fangjie. 2017

[14]Association Analysis between Erythrocyte Membrane Surface Structure and Genes in Cyprinus carpio with Different Vitality at Lower Temperature. Liang, Liqun,Lei, Qingquan,Liang, Liqun,Chang, Yumei. 2009

[15]Differentially gene expression in the brain of common carp (Cyprinus carpio) response to cold acclimation. Liang, Liqun,Li, Shaowu,Chang, Yumei,Li, Yong,Sun, Xiaowen,Liang, Liqun,Lei, Qingquan,Li, Shaowu. 2008

[16]A genetic linkage map of common carp (Cyprinus carpio L.) And mapping of a locus associated with cold tolerance. Sun, XW,Liang, LQ. 2004

[17]Genetic Variability of Koi Herpesvirus In vitro-A Natural Event?. Klafack, Sandro,Bergmann, Sven M.,Wang, Qing,Zeng, Weiwei,Wang, Yingying,Li, Yingying,Zheng, Shucheng,Kempter, Jolanta,Lee, Pei-Yu,Matras, Marek. 2017

[18]Mapping quantitative trait loci for flesh fat content in common carp (Cyprinus carpio). Kuang, Youyi,Zheng, Xianhu,Lv, Weihua,Cao, Dingchen,Sun, Xiaowen,Lv, Weihua.

[19]Cloning, expression analysis, and antibacterial propertiesof three serum amyloid A in common carp (Cyprinus carpio). Yu, Juhua,Tang, Yongkai,Li, Jianlin,Li, Hongxia,Yu, Fan,Yu, Juhua,Yu, Wenjuan,He, Feng,Mao, Shuntao,Fu, Chunjie.

[20]Non-O1 Vibrio cholerae pathogen from Cyprinus carpio and control with anti-non-O1 V. cholerae egg yolk powder (IgY). Gao, Xiaojian,Chen, Nan,Zhang, Yue,Zhang, Xiaojun,Bing, Xuwen.

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国水产科学研究院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台