The HOG-pathway related AaOS1 leads to dicarboximide-resistance in field strains of Alternaria alternata and contributes, together with the Aafhk1, to mycotoxin production and virulence
文献类型： 外文期刊
作者： Wei, Lingling 3 ; Chen, Bin 3 ; Li, Xiujuan 3 ; Shi, Haiping 3 ; Xie, Shuai 3 ; Hu, Hao 3 ; Chen, Wenchan 4 ; Wei, Lihui 4 ; Wang, Xiaoyu 2 ; Chen, Changjun 1 ;
作者机构： 1.Nanjing Agr Univ, Coll Plant Protect, Nanjing 210095, Jiangsu, Peoples R China
2.Jiangsu Acad Agr Sci, Inst Plant Protect, Nanjing 210095, Jiangsu, Peoples R China
3.Nanjing Agr Univ, Coll Plant Protect, Nanjing, Peoples R China
4.Jiangsu Acad Agr Sci, Inst Plant Protect, Nanjing, Peoples R China
关键词： garlic leaf spot; Alternaria alternata; dicarboximides; mutations; mycotoxin AOH
期刊名称：PEST MANAGEMENT SCIENCE （ 影响因子：4.1； 五年影响因子：4.4 ）
ISSN： 1526-498X
年卷期： 2024 年 80 卷 6 期
页码：
收录情况： SCI
摘要： BACKGROUND: Garlic leaf spot (GLS) caused by Alternaria alternata is one of the main diseases in the garlic production areas, and its management heavily relies on dicarboximide fungicides. However, the efficacy of dicarboximides against the GLS disease has decreased year on year. RESULTS: In the present study, 10 of 148 A. alternata strains separated from Jiangsu Province were moderately resistant (MR) to a dicarboximide fungicide procymidone (Pro(MR)). Positive cross-resistance was observed between Pro and iprodione (Ipro) or fludioxonil (Fld), but not between Pro and fluazinam or azoxystrobin. Mutations at AaOS1, but not Aafhk1, were confirmed to confer the Pro resistance by constructing replacement mutants, whereas mutations at both AaOS1 and Aafhk1 decreased the gene expression level of AapksI, as well as the ability to produce mycotoxin AOH (polyketide-derived alternariol) and virulence. Additionally, more genes (AaOS1 and Aafhk1) harboring the mutations experienced a larger biological fitness penalty. CONCLUSION: To our knowledge, this is the first report on Pro resistance selected in garlic fields, and mutations at AaOS1 of A. alternata causing a decreased ability to produce the mycotoxin AOH. (c) 2024 Society of Chemical Industry.
- 相关文献
作者其他论文 更多>>
-
The natural polycyclic tetramate macrolactam HSAF inhibit Fusarium graminearum through altering cell membrane integrity by targeting FgORP1
作者：Chen, Wenchan;Tang, Bao;Hou, Rongxian;Sun, Weibo;Guo, Baodian;Zhao, Yangyang;Li, Chaohui;Sheng, Cong;Zhao, Yancun;Liu, Fengquan;Liu, Fengquan;Han, Chenyang
关键词：F. graminearum; HSAF; FgORP1; Ergosterol; Cell membrane
-
Staurosporine-producing Streptomyces sp. strain 11 x 1 cell-free culture filtrates control diseases caused by the oomycete plant pathogens Pythium myriotylum and Phytophthora sojae
作者：Wen, Xian;Wang, Lunji;Li, Jingjing;Jiu, Min;Wen, Xian;Li, Jingjing;Chen, Yifan;Zhuo, Deyu;Anjago, Wilfred Mabeche;Zhu, Hongli;Zhang, Qimeng;Zhang, Jinfeng;Wang, Xiaoyu;Wei, Lihui;Daly, Paul;Zhou, Dongmei;Chen, Yifan;Wei, Lihui;Peng, Hao;Wang, Lunji;Daly, Paul;Zhou, Dongmei
关键词：Streptomyces; Pythium myriotylum; Phytophthora sojae; Biological control; Ginger; Soybean
-
Functional Plasticity, Redundancy, and Specificity of Lanosterol 14α-Demethylase in Regulating the Sensitivity to DMIs in Calonectria ilicicola
作者：Wei, Lingling;Shi, Haiping;Chen, Bin;Li, Xiujuan;Chen, Changjun;Chen, Wenchan;Wu, Chengdong;Gai, Yunpeng
关键词：C. ilicicola; sterol 14 alpha-demethylase; novel genus-specific CYP51 function; DMI sensitivity; molecular docking
-
A major gene for chilling tolerance variation in Indica rice codes for a kinase OsCTK1 that phosphorylates multiple substrates under cold
作者：Wu, Jiawen;Liu, Huimin;Zhang, Yan;Zhang, Yingdong;Li, Dongling;Liu, Shiyan;Lu, Shan;Zou, Baohong;Liu, Huimin;Zhang, Yan;Wei, Lihui;Hua, Jian
关键词：chilling tolerance; GWAS; haplotype; natural variation; OsCTK1; phosphorylation
-
Resistance mechanism of Phomopsis longicolla to fludioxonil is associated with modifications in PlOS1, PlOS4 and PlOS5
作者：Wei, Lingling;Chen, Bin;Li, Jiawei;Zhang, Pengcheng;Ye, Wenwu;Chen, Changjun;Chen, Wenchan
关键词：P. longicolla; Fludioxonil; Mutation in PlOSs; Hog1 phosphorylation level; Baseline sensitivity; Resistance risk
-
Growth, Enzymatic, and Transcriptomic Analysis of xyr1 Deletion Reveals a Major Regulator of Plant Biomass-Degrading Enzymes in Trichoderma harzianum
作者：Wang, Lunji;Zhao, Yishen;Wen, Xian;Jiu, Min;Zhao, Yishen;Chen, Siqiao;Wen, Xian;Anjago, Wilfred Mabeche;Tian, Tianchi;Chen, Yajuan;Zhang, Jinfeng;Deng, Sheng;Zhou, Dongmei;Wei, Lihui;Daly, Paul;Chen, Siqiao;Chen, Yajuan;Fu, Pengxiao;Druzhinina, Irina S.
关键词：CAZymes; XYR1/XlnR/XLR-1; cellulose; transcriptional regulation
-
Functional Differentiation of the Succinate Dehydrogenase Subunit SdhC Governs the Sensitivity to SDHI Fungicides, ROS Homeostasis, and Pathogenicity in Fusarium asiaticum
作者：Chen, Wenchan;Li, Xiujuan;Wei, Lingling;Chen, Bin;Duan, Yabing;Chen, Changjun;Chen, Wenchan;Han, Chenyang
关键词：F. asiaticum; SdhC subunits; virulence; ROS homeostasis; SDHI sensitivity
